Discovery of Aldisine and Its Derivatives as Novel Antiviral, Larvicidal, and Antiphytopathogenic-Fungus Agents.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.2c04256
Abstract: Based on the widespread use of hydrogen bonds in drug design, a series of aldisine derivatives containing oxime, oxime ether, and hydrazone moieties were designed and synthesized, and their antiviral, larvicidal, and fungicidal activities were… read more here.
Keywords: novel antiviral; discovery aldisine; derivatives novel; antiviral larvicidal ... See more keywords
Topoisomerase II as a Novel Antiviral Target against Panarenaviral Diseases
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DOI: 10.3390/v15010105
Abstract: Although many arenaviruses cause severe diseases with high fatality rates each year, treatment options are limited to off-label use of ribavirin, and a Food and Drug Administration (FDA)-approved vaccine is not available. To identify novel… read more here.
Keywords: topoisomerase novel; novel antiviral; replication; target panarenaviral ... See more keywords