Articles with "novel arylpiperazine" as a keyword



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Synthesis, bioactivity, and molecular docking of novel arylpiperazine derivatives as potential AR antagonists

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Published in 2022 at "Frontiers in Chemistry"

DOI: 10.3389/fchem.2022.947065

Abstract: Prostate cancer is one of the malignant tumors and the second most common malignant tumor in men. Clinically used androgen receptor (AR)–targeted drugs can antagonize androgen and inhibit tumor growth, but these drugs can cause… read more here.

Keywords: molecular docking; arylpiperazine derivatives; novel arylpiperazine; bioactivity molecular ... See more keywords