Novel aspects of age-protection by spermidine supplementation are associated with preserved telomere length
Sign Up to like & getrecommendations! Published in 2021 at "GeroScience"
DOI: 10.1007/s11357-020-00310-0
Abstract: Ageing provokes a plethora of molecular, cellular and physiological deteriorations, including heart failure, neurodegeneration, metabolic maladaptation, telomere attrition and hair loss. Interestingly, on the molecular level, the capacity to induce autophagy, a cellular recycling and… read more here.
Keywords: novel aspects; age; aspects age; age protection ... See more keywords
Apolipoprotein E in Cardiovascular Diseases: Novel Aspects of an Old-fashioned Enigma.
Sign Up to like & getrecommendations! Published in 2018 at "Archives of medical research"
DOI: 10.1016/j.arcmed.2018.08.008
Abstract: The presence of different APOE isoforms represents a well-known risk factor for cardiovascular diseases. Besides the pleiotropic effects of APOE polymorphism on heart and neurological diseases, this review summarizes the less-known functions of APOE and… read more here.
Keywords: novel aspects; old fashioned; cardiovascular diseases; aspects old ... See more keywords
Novel aspects in histopathology of the pituitary gland.
Sign Up to like & getrecommendations! Published in 2017 at "Endocrinologia, diabetes y nutricion"
DOI: 10.1016/j.endinu.2016.10.004
Abstract: The sellar and parasellar region is a complex anatomical area in which several diseases may develop. The pituitary gland may be affected by a wide range of conditions having similar clinical characteristics. Diagnosis of these… read more here.
Keywords: novel aspects; diagnosis; aspects histopathology; histopathology ... See more keywords
Novel aspects of the assembly and activation of inflammasomes with focus on the NLRC4 inflammasome
Sign Up to like & getrecommendations! Published in 2018 at "International Immunology"
DOI: 10.1093/intimm/dxy009
Abstract: Inflammasomes are multiprotein structures that activate caspase-1, support secretion of pro-inflammatory cytokines, IL-1β and IL-18, and also induce inflammatory programmed cell death, termed pyoptosis. Inflammasomes are activated in response to the detection of endogenous and… read more here.
Keywords: novel aspects; aspects assembly; inflammasomes focus; focus nlrc4 ... See more keywords
Novel aspects in the pathophysiology and diagnosis of glomerular diseases
Sign Up to like & getrecommendations! Published in 2022 at "Annals of the Rheumatic Diseases"
DOI: 10.1136/ard-2022-222495
Abstract: Immune deposits/complexes are detected in a multitude of tissues in autoimmune disorders, but no organ has attracted as much attention as the kidney. Several kidney diseases are characterised by the presence of specific configurations of… read more here.
Keywords: immune deposits; aspects pathophysiology; novel aspects; deposits complexes ... See more keywords
Novel Aspects of Renal Magnesium Homeostasis
Sign Up to like & getrecommendations! Published in 2018 at "Frontiers in Pediatrics"
DOI: 10.3389/fped.2018.00077
Abstract: Magnesium (Mg2+) is indispensable for several vital functions, such as neurotransmission, cardiac conductance, blood glucose, blood pressure regulation, and proper function of more than 300 enzymes. Thus, Mg2+ homeostasis is subject to tight regulation. Besides… read more here.
Keywords: homeostasis; novel aspects; physiology; magnesium ... See more keywords
Cell Biology of Galectins: Novel Aspects and Emerging Challenges
Sign Up to like & getrecommendations! Published in 2022 at "Biomolecules"
DOI: 10.3390/biom12060744
Abstract: Galectins are a family of soluble β-galactoside-binding proteins with diverse glycan-dependent and glycan-independent functions outside and inside the cell [...]. read more here.
Keywords: biology galectins; cell biology; novel aspects; galectins novel ... See more keywords
Novel Aspects of the Immune Response Involved in the Peritoneal Damage in Chronic Kidney Disease Patients under Dialysis
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24065763
Abstract: Chronic kidney disease (CKD) incidence is growing worldwide, with a significant percentage of CKD patients reaching end-stage renal disease (ESRD) and requiring kidney replacement therapies (KRT). Peritoneal dialysis (PD) is a convenient KRT presenting benefices… read more here.
Keywords: damage; disease; kidney; chronic kidney ... See more keywords
Novel Aspects of the SubA Subunit of the Subtilase Cytotoxin
Sign Up to like & getrecommendations! Published in 2022 at "Toxins"
DOI: 10.3390/toxins14020156
Abstract: The subtilase cytotoxin (SubAB) belongs to the family of AB5 toxins and is produced together with Shiga toxin (Stx) by certain Stx-producing E. coli strains (STEC). For most AB-type toxins, it is assumed that cytotoxic… read more here.
Keywords: aspects suba; subtilase; novel aspects; suba ... See more keywords