Assessment of novel azaanthraquinone derivatives as potent multi-target inhibitors of inflammation and amyloid-β aggregation in Alzheimer's disease.
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DOI: 10.1016/j.bioorg.2018.10.073
Abstract: A series of 6-substituted azaanthraquinone derivatives have been designed, synthesized, and their anti-inflammatory activities, antiaggregation effects on β-amyloid proteins, anticholinesterase and neuroprotective activity were tested. The new derivatives strongly suppressed NO and iNOS production and… read more here.
Keywords: novel azaanthraquinone; aggregation; derivatives potent; potent multi ... See more keywords