Design, Synthesis, and Evaluation of a Series of Novel Benzocyclobutene Derivatives as General Anesthetics.
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DOI: 10.1021/acs.jmedchem.7b00253
Abstract: In the present work, a series of structurally novel benzocyclobutene derivatives were identified as general anesthetics through the loss of righting reflex (LORR) experiment on mice. Our initial efforts found compound 1a with a fused… read more here.
Keywords: design synthesis; series; benzocyclobutene derivatives; general anesthetics ... See more keywords