Metabolic Dysfunction in New‐Onset Idiopathic Intracranial Hypertension: Identification of Novel Biomarkers
Sign Up to like & getrecommendations! Published in 2024 at "Annals of Neurology"
DOI: 10.1002/ana.27010
Abstract: Idiopathic intracranial hypertension (IIH) is a neurometabolic disease with an increasing incidence. The pathophysiology is unknown, but improvement of diagnosis and management requires discovery of novel biomarkers. Our objective was to identify such candidate biomarkers… read more here.
Keywords: intracranial hypertension; novel biomarkers; idiopathic intracranial; dysfunction new ... See more keywords
Novel Biomarkers for Improving the Diagnosis of Appendicitis in Pediatric Patients
Sign Up to like & getrecommendations! Published in 2025 at "Journal of Clinical Laboratory Analysis"
DOI: 10.1002/jcla.70048
Abstract: Diagnosing appendicitis in pediatric patients remains a clinical challenge, especially in resource‐limited settings where imaging tools are less accessible. Inflammatory markers, including the Neutrophil‐to‐Lymphocyte Ratio (NLR), Monocyte‐to‐Lymphocyte Ratio (MLR), Neutrophil‐to‐Monocyte Ratio (NMR), Platelet‐to‐Lymphocyte Ratio (PLR),… read more here.
Keywords: pediatric patients; novel biomarkers; appendicitis pediatric; lymphocyte ratio ... See more keywords
Identification of novel biomarkers and small molecule drugs in human colorectal cancer by microarray and bioinformatics analysis
Sign Up to like & getrecommendations! Published in 2019 at "Molecular Genetics & Genomic Medicine"
DOI: 10.1002/mgg3.713
Abstract: Colorectal cancer (CRC) is one of the most common malignant tumors. In the present study, the expression profile of human multistage colorectal mucosa tissues, including healthy, adenoma, and adenocarcinoma samples was downloaded to identify critical… read more here.
Keywords: small molecule; colorectal cancer; novel biomarkers; identification novel ... See more keywords
Chitinase 3-Like 1, Nestin, and Testin Proteins as Novel Biomarkers of Potential Clinical Use in Colorectal Cancer: A Review.
Sign Up to like & getrecommendations! Published in 2020 at "Advances in experimental medicine and biology"
DOI: 10.1007/5584_2020_506
Abstract: Colorectal cancer is the third most commonly diagnosed cancer in males and the second most common in females. Only 10-20% of patients are diagnosed at the early stage of disease. Recently, the role of novel… read more here.
Keywords: biomarkers potential; colorectal cancer; testin; novel biomarkers ... See more keywords
Novel biomarkers for the evaluation of aging-induced proteinopathies
Sign Up to like & getrecommendations! Published in 2020 at "Biogerontology"
DOI: 10.1007/s10522-020-09878-8
Abstract: Proteinopathies are characterized by aging related accumulation of misfolded protein aggregates. Irreversible covalent modifications of aging proteins may significantly affect the native three dimentional conformation of proteins, alter their function and lead to accumulation of… read more here.
Keywords: accumulation; aging induced; biomarkers evaluation; induced proteinopathies ... See more keywords
Heart Failure in Breast Cancer Survivors: Focus on Early Detection and Novel Biomarkers
Sign Up to like & getrecommendations! Published in 2021 at "Current Heart Failure Reports"
DOI: 10.1007/s11897-021-00535-w
Abstract: Breast cancer survival rate has greatly improved in the last two decades due to the emergence of next-generation anti-cancer agents. However, cardiotoxicity remains a significant adverse effect arising from traditional and emerging chemotherapies as well… read more here.
Keywords: detection; breast cancer; novel biomarkers; cardiotoxicity ... See more keywords
Novel Biomarkers in Sinonasal Cancers: from Bench to Bedside
Sign Up to like & getrecommendations! Published in 2020 at "Current Oncology Reports"
DOI: 10.1007/s11912-020-00947-2
Abstract: Sinonasal cancers are a heterogenous group of rare cancers for which histopathological diagnosis can be very challenging and treatment options are limited for advanced disease in particular. Here, we review the candidacy of novel diagnostic… read more here.
Keywords: cancers bench; sinonasal cancers; novel biomarkers; bench bedside ... See more keywords
Identifying Novel Biomarkers Ready for Evaluation in Low-Prevalence Populations for the Early Detection of Upper Gastrointestinal Cancers: A Systematic Review
Sign Up to like & getrecommendations! Published in 2020 at "Advances in Therapy"
DOI: 10.1007/s12325-020-01571-z
Abstract: Detecting upper gastrointestinal (GI) cancers in primary care is challenging, as cancer symptoms are common, often non-specific, and most patients presenting with these symptoms will not have cancer. Substantial investment has been made to develop… read more here.
Keywords: prevalence populations; detection; low prevalence; novel biomarkers ... See more keywords
Novel biomarkers for sepsis: A narrative review.
Sign Up to like & getrecommendations! Published in 2017 at "European journal of internal medicine"
DOI: 10.1016/j.ejim.2017.09.030
Abstract: BACKGROUND Sepsis is a prevalent condition among hospitalized patients that carries a high risk of morbidity and mortality. Rapid recognition of sepsis as the cause of deterioration is desirable, so effective treatment can be initiated… read more here.
Keywords: sepsis; narrative review; sepsis narrative; biomarkers sepsis ... See more keywords
Screening and Validation of Novel Biomarkers in Osteoarticular Pathologies by Comprehensive Combination of Protein Array Technologies.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of proteome research"
DOI: 10.1021/acs.jproteome.6b00980
Abstract: Osteoarthritis (OA) is one of the most prevalent articular diseases. The identification of proteins closely associated with the diagnosis, progression, prognosis, and treatment response is dramatically required for this pathology. In this work, differential serum… read more here.
Keywords: protein; validation novel; biomarkers osteoarticular; osteoarticular pathologies ... See more keywords
Integration of novel biomarkers in prospective trials: biological insights from CHOICE-01
Sign Up to like & getrecommendations! Published in 2024 at "Signal Transduction and Targeted Therapy"
DOI: 10.1038/s41392-024-02078-7
Abstract: The recent publication of the CHOICE-01 study, reporting overall survival (OS) and published in Signal Transduction and Targeted Therapy , 1 recapitulated fi ndings from an earlier publication of the trial. 2 The CHOICE-01 investigators… read more here.
Keywords: lung cancer; novel biomarkers; integration novel; choice ... See more keywords