Identification of novel biomarkers and small molecule drugs in human colorectal cancer by microarray and bioinformatics analysis
Sign Up to like & getrecommendations! Published in 2019 at "Molecular Genetics & Genomic Medicine"
DOI: 10.1002/mgg3.713
Abstract: Colorectal cancer (CRC) is one of the most common malignant tumors. In the present study, the expression profile of human multistage colorectal mucosa tissues, including healthy, adenoma, and adenocarcinoma samples was downloaded to identify critical… read more here.
Keywords: small molecule; colorectal cancer; novel biomarkers; identification novel ... See more keywords
Chitinase 3-Like 1, Nestin, and Testin Proteins as Novel Biomarkers of Potential Clinical Use in Colorectal Cancer: A Review.
Sign Up to like & getrecommendations! Published in 2020 at "Advances in experimental medicine and biology"
DOI: 10.1007/5584_2020_506
Abstract: Colorectal cancer is the third most commonly diagnosed cancer in males and the second most common in females. Only 10-20% of patients are diagnosed at the early stage of disease. Recently, the role of novel… read more here.
Keywords: biomarkers potential; colorectal cancer; testin; novel biomarkers ... See more keywords
Novel biomarkers for the evaluation of aging-induced proteinopathies
Sign Up to like & getrecommendations! Published in 2020 at "Biogerontology"
DOI: 10.1007/s10522-020-09878-8
Abstract: Proteinopathies are characterized by aging related accumulation of misfolded protein aggregates. Irreversible covalent modifications of aging proteins may significantly affect the native three dimentional conformation of proteins, alter their function and lead to accumulation of… read more here.
Keywords: accumulation; aging induced; biomarkers evaluation; induced proteinopathies ... See more keywords
Heart Failure in Breast Cancer Survivors: Focus on Early Detection and Novel Biomarkers
Sign Up to like & getrecommendations! Published in 2021 at "Current Heart Failure Reports"
DOI: 10.1007/s11897-021-00535-w
Abstract: Breast cancer survival rate has greatly improved in the last two decades due to the emergence of next-generation anti-cancer agents. However, cardiotoxicity remains a significant adverse effect arising from traditional and emerging chemotherapies as well… read more here.
Keywords: detection; breast cancer; novel biomarkers; cardiotoxicity ... See more keywords
Novel Biomarkers in Sinonasal Cancers: from Bench to Bedside
Sign Up to like & getrecommendations! Published in 2020 at "Current Oncology Reports"
DOI: 10.1007/s11912-020-00947-2
Abstract: Sinonasal cancers are a heterogenous group of rare cancers for which histopathological diagnosis can be very challenging and treatment options are limited for advanced disease in particular. Here, we review the candidacy of novel diagnostic… read more here.
Keywords: cancers bench; sinonasal cancers; novel biomarkers; bench bedside ... See more keywords
Identifying Novel Biomarkers Ready for Evaluation in Low-Prevalence Populations for the Early Detection of Upper Gastrointestinal Cancers: A Systematic Review
Sign Up to like & getrecommendations! Published in 2020 at "Advances in Therapy"
DOI: 10.1007/s12325-020-01571-z
Abstract: Detecting upper gastrointestinal (GI) cancers in primary care is challenging, as cancer symptoms are common, often non-specific, and most patients presenting with these symptoms will not have cancer. Substantial investment has been made to develop… read more here.
Keywords: prevalence populations; detection; low prevalence; novel biomarkers ... See more keywords
Novel biomarkers for sepsis: A narrative review.
Sign Up to like & getrecommendations! Published in 2017 at "European journal of internal medicine"
DOI: 10.1016/j.ejim.2017.09.030
Abstract: BACKGROUND Sepsis is a prevalent condition among hospitalized patients that carries a high risk of morbidity and mortality. Rapid recognition of sepsis as the cause of deterioration is desirable, so effective treatment can be initiated… read more here.
Keywords: sepsis; narrative review; sepsis narrative; biomarkers sepsis ... See more keywords
Screening and Validation of Novel Biomarkers in Osteoarticular Pathologies by Comprehensive Combination of Protein Array Technologies.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of proteome research"
DOI: 10.1021/acs.jproteome.6b00980
Abstract: Osteoarthritis (OA) is one of the most prevalent articular diseases. The identification of proteins closely associated with the diagnosis, progression, prognosis, and treatment response is dramatically required for this pathology. In this work, differential serum… read more here.
Keywords: protein; validation novel; biomarkers osteoarticular; osteoarticular pathologies ... See more keywords
Existing and novel biomarkers for precision medicine in systemic sclerosis
Sign Up to like & getrecommendations! Published in 2018 at "Nature Reviews Rheumatology"
DOI: 10.1038/s41584-018-0021-9
Abstract: The discovery and validation of biomarkers resulting from technological advances in the analysis of genomic, transcriptomic, lipidomic and metabolomic pathways involved in the pathogenesis of complex human diseases have led to the development of personalized… read more here.
Keywords: medicine; ssc; response; systemic sclerosis ... See more keywords
Proteome profiling reveals novel biomarkers to identify complicated parapneumonic effusions
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-04189-4
Abstract: Patients with pneumonia and parapneumonic effusion (PPE) have elevated mortality and a poor prognosis. The aim of this study was to discover novel biomarkers to help distinguish between uncomplicated PPE (UPPE) and complicated PPE (CPPE).… read more here.
Keywords: reveals novel; profiling reveals; identify complicated; biomarkers identify ... See more keywords
Untargeted LC-HRMS-based metabolomics to identify novel biomarkers of metastatic colorectal cancer
Sign Up to like & getrecommendations! Published in 2019 at "Scientific Reports"
DOI: 10.1038/s41598-019-55952-8
Abstract: Colorectal cancer is one of the main causes of cancer death worldwide, and novel biomarkers are urgently needed for its early diagnosis and treatment. The utilization of metabolomics to identify and quantify metabolites in body… read more here.
Keywords: metastatic colorectal; metabolomics identify; colorectal cancer; untargeted hrms ... See more keywords