A novel bivalent fusion vaccine induces broad immunoprotection against Staphylococcus aureus infection in different murine models.
Sign Up to like & getrecommendations! Published in 2018 at "Clinical immunology"
DOI: 10.1016/j.clim.2017.12.012
Abstract: With more and more drug-resistant Staphylococcus aureus strains emerging in hospitals, there is an urgent need to develop an effective vaccine to combat S. aureus infection. In this study, we constructed a novel bivalent fusion… read more here.
Keywords: aureus infection; fusion vaccine; staphylococcus aureus; novel bivalent ... See more keywords
Synthesis and In Vitro Antitumor Activity of Novel Bivalent β-Carboline-3-carboxylic Acid Derivatives with DNA as a Potential Target
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DOI: 10.3390/ijms19103179
Abstract: A series of novel bivalent β-carboline derivatives were designed and synthesized, and in vitro cytotoxicity, cell apoptosis, and DNA-binding affinity were evaluated. The cytotoxic results demonstrated that most bivalent β-carboline derivatives exhibited stronger cytotoxicity than… read more here.
Keywords: antitumor activity; novel bivalent; carboline; bivalent carboline ... See more keywords
Engineering a Novel Bivalent Oral Vaccine against Enteric Fever
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DOI: 10.3390/ijms22063287
Abstract: Enteric fever is a major global healthcare issue caused largely by Salmonella enterica serovars Typhi and Paratyphi A. The objective of this study was to develop a novel, bivalent oral vaccine capable of protecting against… read more here.
Keywords: engineering; oral vaccine; bivalent oral; enteric fever ... See more keywords