Vitamin K: A novel cancer chemosensitizer
Sign Up to like & getrecommendations! Published in 2022 at "Biotechnology and Applied Biochemistry"
DOI: 10.1002/bab.2312
Abstract: Cancer incidences are growing rapidly and causing millions of deaths globally. Cancer treatment is one of the most exigent challenges. Drug resistance is a natural phenomenon and is considered one of the major obstacles in… read more here.
Keywords: cancer chemosensitizer; novel cancer; vitamin novel; cancer ... See more keywords
The evidence base of US Food and Drug Administration approvals of novel cancer therapies from 2000 to 2020
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Cancer"
DOI: 10.1002/ijc.34473
Abstract: Concerns have been raised that regulatory programs to accelerate approval of cancer drugs in cancer may increase uncertainty about benefits and harms for survival and quality of life (QoL). We analyzed all pivotal clinical trials… read more here.
Keywords: cancer; evidence base; novel cancer; cancer drugs ... See more keywords
Clinical effectiveness reporting of novel cancer drugs in the context of non-proportional hazards: a review of nice single technology appraisals
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Technology Assessment in Health Care"
DOI: 10.1017/s0266462323000119
Abstract: Abstract Objectives The hazard ratio (HR) is a commonly used summary statistic when comparing time to event (TTE) data between trial arms, but assumes the presence of proportional hazards (PH). Non-proportional hazards (NPH) are increasingly… read more here.
Keywords: proportional hazards; methodology; novel cancer; clinical effectiveness ... See more keywords
Abstract 4931: Novel cancer suppressing role of REIC/DKK3 protein through a downregulation of cell surface PD-L1 in breast cancer cells
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Research"
DOI: 10.1158/1538-7445.am2023-4931
Abstract: Adenovirus vector carrying REIC gene (Ad-REIC) is currently in clinical evaluation. The anti-cancer effect of Ad-REIC is mainly caused by two ways, cancer specific apoptosis via endoplasmic reticulum stress with an abundant REIC protein and… read more here.
Keywords: role; cancer suppressing; novel cancer; reic ... See more keywords
Novel cancer therapies and their association with diabetes.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of molecular endocrinology"
DOI: 10.1530/jme-18-0002
Abstract: Over the last decade, there has been a shift in the focus of cancer therapy from conventional cytotoxic drugs to therapies more specifically directed to cancer cells. These novel therapies include immunotherapy, targeted therapy and… read more here.
Keywords: medicine; association diabetes; therapies association; cancer therapies ... See more keywords
Novel cancer therapy targeting microbiome
Sign Up to like & getrecommendations! Published in 2019 at "OncoTargets and therapy"
DOI: 10.2147/ott.s207546
Abstract: Abstract In the human intestinal tract, there are more than 100 trillion symbiotic bacteria, which form the gut microbiota. Approximately 70% of the human immune system is in the intestinal tract, which prevents infection by… read more here.
Keywords: microbiota; cancer; cancer therapy; therapy targeting ... See more keywords
Editorial: Novel Cancer Treatments Based on Autophagy Modulation
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2021.650559
Abstract: IMDEA Nanociencia, Ciudad Universitaria de Cantoblanco, Madrid, Spain, Department of Experimental Medicine, Sapienza University of Rome, Rome, Italy, Department of Neurosciences, Biomedicine and Movement Sciences, Section of Biochemistry, University of Verona, Verona, Italy, Department of… read more here.
Keywords: based autophagy; autophagy modulation; treatments based; cancer treatments ... See more keywords
Recent Trends in Biosensing and Diagnostic Methods for Novel Cancer Biomarkers
Sign Up to like & getrecommendations! Published in 2023 at "Biosensors"
DOI: 10.3390/bios13030398
Abstract: Cancer is one of the major public health issues in the world. It has become the second leading cause of death, with approximately 75% of cancer deaths transpiring in low- or middle-income countries. It causes… read more here.
Keywords: recent trends; diagnostic methods; novel cancer; biosensing diagnostic ... See more keywords
Piloting a novel cancer care pathway: socioeconomic background as a barrier to access.
Sign Up to like & getrecommendations! Published in 2022 at "Clinical medicine"
DOI: 10.7861/clinmed.2021-0716
Abstract: BACKGROUND The multidisciplinary diagnostic clinic (MDC) model for 'non-specific' symptoms has been piloted in the UK. We aimed to assess the degree to which the MDC pathway was influenced by socioeconomic factors. METHODS We collected… read more here.
Keywords: mdc pathway; piloting novel; background; novel cancer ... See more keywords