In Search of Novel CDK8 Inhibitors by Virtual Screening
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DOI: 10.1021/acs.jcim.6b00711
Abstract: Aberrant activity of cyclin-dependent kinase (CDK) 8 is implicated in various cancers. While CDK8-targeting anticancer drugs are highly sought-after, no CDK8 inhibitor has yet reached clinical trials. Herein a large library of drug-like molecules was… read more here.
Keywords: virtual screening; cdk8 inhibitors; search novel; cdk8 ... See more keywords