Establishment and characterization of a novel cell line, NCC-TGCT1-C1, derived from a patient with tenosynovial giant cell tumor
Sign Up to like & getrecommendations! Published in 2020 at "Human Cell"
DOI: 10.1007/s13577-020-00425-8
Abstract: Tenosynovial giant cell tumor (TGCT) is a mesenchymal tumor arising from the synovium of tendon sheath and joints, characterized by translocation t(1;2)(p13;q37). Clinical behaviors of TGCT range from favorable to locally aggressive and further research… read more here.
Keywords: cell line; novel cell; ncc tgct1; cell ... See more keywords
Establishment of a novel, cell-based autotaxin assay.
Sign Up to like & getrecommendations! Published in 2021 at "Analytical biochemistry"
DOI: 10.1016/j.ab.2021.114322
Abstract: Autotaxin (ATX) plays an important role in (patho-)physiological lysophosphatidic acid (LPA) signaling. Here we describe the establishment of novel cell-based ATX assay formats. ATX-mediated LPA generation is detected by using a stable LPA receptor reporter… read more here.
Keywords: atx; autotaxin; novel cell; cell based ... See more keywords
Identification of novel B-cell epitopes on the capsid protein of type 1 porcine astrovirus, using monoclonal antibodies.
Sign Up to like & getrecommendations! Published in 2021 at "International journal of biological macromolecules"
DOI: 10.1016/j.ijbiomac.2021.08.129
Abstract: Porcine astrovirus (PAstV) is prevalent in pigs worldwide and could cause clinical symptoms such as diarrhea and encephalitis. The capsid protein (Cap) of PAstV plays a determinant role for virus immunological characteristics. In this study,… read more here.
Keywords: cell epitopes; monoclonal antibodies; novel cell; capsid protein ... See more keywords
A novel cell-based strategy based on MHCI/CD90 expression levels for highly proliferative MSC identification
Sign Up to like & getrecommendations! Published in 2020 at "Cytotherapy"
DOI: 10.1016/j.jcyt.2020.03.183
Abstract: Background & Aim Mesenchymal stromal cells (MSCs) are of clinical interest because of their validated safety profile and their tremendous biological properties. Nonetheless, variable clinical outcomes have been reported in the literature. Non-reproducible results are… read more here.
Keywords: mhci; novel cell; cell based; expression levels ... See more keywords
A Novel Cell-Assisted Enhanced Chemiluminescence Strategy for Rapid and Label-Free Detection of Tumor Cells in Whole Blood.
Sign Up to like & getrecommendations! Published in 2020 at "ACS sensors"
DOI: 10.1021/acssensors.9b02140
Abstract: In this study, an interesting phenomenon was found that cells (including tumor and normal cells) managed to signifi-cantly enhance chemiluminescence (CL) signals. The possible reaction mechanism may be that cells can be severely dam-aged by… read more here.
Keywords: detection; tumor cells; novel cell; cell assisted ... See more keywords
Simulation of novel cell-like topological structures with quantum walk
Sign Up to like & getrecommendations! Published in 2020 at "European Physical Journal Plus"
DOI: 10.1140/epjp/s13360-020-00641-z
Abstract: We demonstrate how quantum walk can simulate exotic cell-like structures for topological phases and boundary states. These cell-like structures contain the three known boundary states of Dirac cone, Fermi arc and flat bands alongside of… read more here.
Keywords: cell like; quantum walk; like topological; novel cell ... See more keywords
Abstract 3274: Novel cell-based bioassays for mono- and multi-specific antibodies targeting PD-1/PD-L1 for combination immunotherapy
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Research"
DOI: 10.1158/1538-7445.am2023-3274
Abstract: Programmed cell death protein 1 (PD-1) is an immune checkpoint (IC) receptor that negatively regulates T cell function. Blocking the interaction of PD-1 with its ligands PD-L1 or PD-L2 unleashes the immune system and enhances… read more here.
Keywords: cell; novel cell; combination; receptor ... See more keywords
Venetoclax: A novel B-cell lymphoma-2 inhibitor for chronic lymphocytic leukemia and other hematologic malignancies
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Oncology Pharmacy Practice"
DOI: 10.1177/1078155217718383
Abstract: Patients with chronic lymphocytic leukemia with the 17p deletion have a poor prognosis and treatment options are limited. Venetoclax, a novel B-cell lymphoma-2 inhibitor, has been approved for treatment-experienced chronic lymphocytic leukemia patients with the… read more here.
Keywords: lymphocytic leukemia; novel cell; venetoclax novel; chronic lymphocytic ... See more keywords
Novel cell-based system to assay cell-cell fusion during myotube formation.
Sign Up to like & getrecommendations! Published in 2022 at "Biomedical research"
DOI: 10.2220/biomedres.43.107
Abstract: A live assay tool has been established to uncover the precise molecular mechanisms underlying complex cell fusion events in myoblasts. The novel cell-based assay, HiMy (HiBiT-based myoblast fusion), utilizes a recently developed split-luciferase technology. The… read more here.
Keywords: cell based; cell; fusion; novel cell ... See more keywords
Plasmacytoid Dendritic Cells as a Novel Cell-Based Cancer Immunotherapy
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms231911397
Abstract: Plasmacytoid dendritic cells (pDCs) are multifaceted immune cells with a wide range of innate and adaptive immunological functions. They constitute the first line of defence against multiple viral infections and have also been reported to… read more here.
Keywords: novel cell; cells novel; plasmacytoid dendritic; dendritic cells ... See more keywords
Developments in marine invertebrate primary culture reveal novel cell morphologies in the model bivalve Crassostrea gigas
Sign Up to like & getrecommendations! Published in 2020 at "PeerJ"
DOI: 10.7717/peerj.9180
Abstract: Cell culture provides useful model systems used in a wide range of biological applications, but its utility in marine invertebrates is limited due to the lack of immortalised cell lines. Primary cell and tissue cultures… read more here.
Keywords: cell morphologies; novel cell; marine invertebrate; culture ... See more keywords