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Published in 2019 at "Journal of medicinal chemistry"
DOI: 10.1021/acs.jmedchem.8b02008
Abstract: Since the discovery of compound BIX01294 over 10 years ago, only a very limited number of nonquinazoline inhibitors of H3K9-specific methyltransferases G9a and G9a-like protein (GLP) have been reported. Herein, we report the identification of…
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Keywords:
crystal structure;
glp;
discovery;
novel chemotype ... See more keywords