Genome based evolutionary lineage of SARS-CoV-2 towards the development of novel chimeric vaccine
Sign Up to like & getrecommendations! Published in 2020 at "Infection, Genetics and Evolution"
DOI: 10.1016/j.meegid.2020.104517
Abstract: The present study aimed to predict a novel chimeric vaccine by simultaneously targeting four major structural proteins via the establishment of ancestral relationship among different strains of coronaviruses. Conserved regions from the homologous protein sets… read more here.
Keywords: vaccine; genome based; novel chimeric; chimeric vaccine ... See more keywords
Phase II Study of Ensituximab, a Novel Chimeric Monoclonal Antibody, in Adults with Unresectable, Metastatic Colorectal Cancer
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DOI: 10.1158/1078-0432.ccr-20-0426
Abstract: Purpose: Patients with metastatic colorectal cancer refractory to chemotherapy have limited treatment options. Ensituximab (NEO-102) is a novel chimeric mAb targeting a variant of MUC5AC with specificity to colorectal cancer. Patients and Methods: Single-arm, phase… read more here.
Keywords: novel chimeric; cancer; metastatic colorectal; colorectal cancer ... See more keywords
Development of a Novel Chimeric Endolysin, Lys109 With Enhanced Lytic Activity Against Staphylococcus aureus
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2020.615887
Abstract: As the incidence of antibiotic-resistant bacteria has become increased, phage endolysins are believed as one of the promising alternatives to antibiotics. However, the discovery of potent endolysin is still challenging because it is labor intensive… read more here.
Keywords: chimeric endolysin; lys109; lytic activity; novel chimeric ... See more keywords
Novel Chimeric Vaccine Candidate Development against Leptotrichia buccalis
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DOI: 10.3390/ijerph191710742
Abstract: The misuse of antibiotics in our daily lives has led to the emergence of antimicrobial resistance. As a result, many antibiotics are becoming ineffective. This phenomenon is linked with high rates of mortality and morbidity.… read more here.
Keywords: leptotrichia buccalis; novel chimeric; chimeric vaccine; vaccine ... See more keywords