Synthesis of some novel chloro-/aryl-substituted-5,5-dimethyl-2-cyclohexenones
Sign Up to like & getrecommendations! Published in 2020 at "Synthetic Communications"
DOI: 10.1080/00397911.2020.1723108
Abstract: Abstract Two novel structural isomers: the dihalo-5,5-dimethyl-2-cyclohexenones were synthesized. Regioselective Suzuki-Miyaura cross coupling reaction of the isomers with nine different aryl boronic acids afforded eighteen novel compounds: the 2-aryl-3-chloro-5,5-dimethyl-2-cyclohexenones and the 3-aryl-2-chloro-5,5-dimethyl-2-cyclohexenones in 90–95% yields,… read more here.
Keywords: chloro aryl; synthesis novel; aryl substituted; novel chloro ... See more keywords
Novel Chloro-Substituted Salicylanilide Derivatives and Their β-Cyclodextrin Complexes: Synthesis, Characterization, and Antibacterial Activity
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DOI: 10.3390/biomedicines10071740
Abstract: The goal of this research was to design novel chloro-substituted salicylanilide derivatives and their β-cyclodextrin complexes in order to obtain efficient antibacterial compounds and to demonstrate the beneficial role of complexation on the efficiency of… read more here.
Keywords: salicylanilide derivatives; activity; derivatives cyclodextrin; substituted salicylanilide ... See more keywords
Novel 7-Chloro-4-aminoquinoline-benzimidazole Hybrids as Inhibitors of Cancer Cells Growth: Synthesis, Antiproliferative Activity, in Silico ADME Predictions, and Docking
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DOI: 10.3390/molecules28020540
Abstract: In this study, new 7-chloro-4-aminoquinoline-benzimidazole compounds were synthesized and characterized by NMR, MS, and elemental analysis. These novel hybrids differ in the type of linker and in the substituent on the benzimidazole moiety. Their antiproliferative… read more here.
Keywords: chloro aminoquinoline; aminoquinoline benzimidazole; adme; activity ... See more keywords