Artificial Intelligence-Enabled De Novo Design of Novel Compounds that Are Synthesizable.
Sign Up to like & getrecommendations! Published in 2022 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-1787-8_17
Abstract: Development of computer-aided de novo design methods to discover novel compounds in a speedy manner to treat human diseases has been of interest to drug discovery scientists for the past three decades. In the beginning, the… read more here.
Keywords: intelligence enabled; enabled novo; artificial intelligence; novo design ... See more keywords
Crystal structures and magnetic properties of novel compounds Sc2CoIn and Sc100Co25In7
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Alloys and Compounds"
DOI: 10.1016/j.jallcom.2017.10.023
Abstract: Abstract Crystal structures of two novel scandium-rich ternary compounds forming in the Sc-Co-In system, obtained by arc-melting of pure metals, were determined using X-ray powder diffraction. The structure of Sc 2 CoIn (space group P… read more here.
Keywords: structures magnetic; compounds sc2coin; magnetic properties; crystal structures ... See more keywords
Novel Compounds as S1P5 Modulators for Treating Neurodegenerative Diseases.
Sign Up to like & getrecommendations! Published in 2024 at "ACS medicinal chemistry letters"
DOI: 10.1021/acsmedchemlett.4c00178
Abstract: Provided herein are novel compounds as S1P5 modulators, pharmaceutical compositions, use of such compounds in treating neurodegenerative diseases, particularly Alzheimer's disease, multiple sclerosis, migraine and amyotrophic lateral sclerosis, and processes for preparing such compounds. read more here.
Keywords: treating neurodegenerative; modulators treating; neurodegenerative diseases; compounds s1p5 ... See more keywords
Novel Compounds as 5-HT2A Agonists for Treating Mental Illness or CNS Disorders.
Sign Up to like & getrecommendations! Published in 2025 at "ACS medicinal chemistry letters"
DOI: 10.1021/acsmedchemlett.5c00066
Abstract: Provided herein are novel compounds as 5-HT2A agonists, pharmaceutical compositions, use of such compounds in treating mental illness or CNS disorders and processes for preparing such compounds. read more here.
Keywords: mental illness; treating mental; ht2a agonists; compounds ht2a ... See more keywords
Novel Compounds as 5‑HT2A Agonists for Treating Mental Illness or CNS Disorders.
Sign Up to like & getrecommendations! Published in 2025 at "ACS medicinal chemistry letters"
DOI: 10.1021/acsmedchemlett.5c00389
Abstract: Provided herein are novel compounds as 5-HT2A agonists, pharmaceutical compositions, use of such compounds in treating mental illness or CNS disorders, and processes for preparing such compounds. read more here.
Keywords: mental illness; treating mental; ht2a agonists; compounds ht2a ... See more keywords
Novel Compounds as TREM2 Agonists for Treating Alzheimer's Disease.
Sign Up to like & getrecommendations! Published in 2025 at "ACS medicinal chemistry letters"
DOI: 10.1021/acsmedchemlett.5c00616
Abstract: Provided herein are novel compounds as TREM2 agonists, pharmaceutical compositions, use of such compounds in treating Alzheimer's disease, and processes for preparing such compounds. read more here.
Keywords: alzheimer disease; compounds trem2; treating alzheimer; novel compounds ... See more keywords
Novel Compounds as ACC Inhibitors for Treating Acne
Sign Up to like & getrecommendations! Published in 2025 at "ACS Medicinal Chemistry Letters"
DOI: 10.1021/acsmedchemlett.5c00663
Abstract: Provided herein are novel compounds as ACC inhibitors, pharmaceutical compositions, use of such compounds in treating acne, and processes for preparing such compounds. read more here.
Keywords: compounds acc; acc inhibitors; inhibitors treating; novel compounds ... See more keywords
Novel Compounds as PI3Kalpha Inhibitors for Treating Cancer
Sign Up to like & getrecommendations! Published in 2025 at "ACS Medicinal Chemistry Letters"
DOI: 10.1021/acsmedchemlett.5c00664
Abstract: Provided herein are novel compounds as PI3Kα inhibitors, pharmaceutical compositions, use of such compounds in treating cancer, and processes for preparing such compounds. read more here.
Keywords: compounds pi3kalpha; treating cancer; pi3kalpha inhibitors; inhibitors treating ... See more keywords
Trying to make it work: Compositional effects in the processing of compound “nonwords”
Sign Up to like & getrecommendations! Published in 2020 at "Quarterly Journal of Experimental Psychology"
DOI: 10.1177/1747021820902019
Abstract: Speakers of languages with synchronically productive compounding systems, such as English, are likely to encounter new compounds on a daily basis. These can only be useful for communication if speakers are able to rapidly compose… read more here.
Keywords: trying make; make work; compositional process; compositional effects ... See more keywords
Synthesis of 1,4-Dioxaspiro[4.4] and 1,4-Dioxaspiro[4.5] Novel Compounds from Oleic Acid as Potential Biolubricant
Sign Up to like & getrecommendations! Published in 2017 at "Indonesian Journal of Chemistry"
DOI: 10.22146/ijc.24891
Abstract: Two 1,4-dioxaspiro novel compounds which derivated from methyl 9,10-dihydroxyoctadecanoate (MDHO) with cyclopentanone and cyclohexanone had been synthesized by a sonochemical method in the presence of montmorillonite KSF catalyst. The MDHO compound had been prepared from… read more here.
Keywords: novel compounds; dioxaspiro; oleic acid; dioxaspiro novel ... See more keywords
Evaluation of novel compounds as anti-bacterial or anti-virulence agents
Sign Up to like & getrecommendations! Published in 2024 at "Frontiers in Cellular and Infection Microbiology"
DOI: 10.3389/fcimb.2024.1370062
Abstract: Antimicrobial resistance is a global threat, leading to an alarming increase in the prevalence of bacterial infections that can no longer be treated with available antibiotics. The World Health Organization estimates that by 2050 up… read more here.
Keywords: evaluation novel; anti bacterial; bacterial anti; anti virulence ... See more keywords