Articles with "novel crbn" as a keyword



Discovery of potential novel CRBN modulators by virtual screening and bioassay.

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Published in 2022 at "European journal of medicinal chemistry"

DOI: 10.1016/j.ejmech.2022.114355

Abstract: The incidence of malignant tumor with high mortality is increasing yearly. CRBN E3 ubiquitin ligase was proved to be an antitumor target. It was found that thalidomide and its analogs could bind to CRBN E3… read more here.

Keywords: modulators virtual; crbn; virtual screening; crbn modulators ... See more keywords