Novel curcumin analogs act as antagonists to control nosocomial infection causing Pseudomonas aeruginosa
Sign Up to like & getrecommendations! Published in 2019 at "Biocatalysis and Agricultural Biotechnology"
DOI: 10.1016/j.bcab.2019.101238
Abstract: Abstract Pseudomonas aeruginosa has become the important cause of hospital acquired nosocomial infection which is one of the leading cause of death in today's world. Here, we synthesized structurally similar analogs of curcumin (G0-G4) as… read more here.
Keywords: curcumin analogs; novel curcumin; pseudomonas aeruginosa; nosocomial infection ... See more keywords
The AMPA receptor biophysical gating properties and binding site: Focus on novel curcumin-based diazepines as non-competitive antagonists.
Sign Up to like & getrecommendations! Published in 2021 at "Bioorganic chemistry"
DOI: 10.1016/j.bioorg.2021.105406
Abstract: INTRODUCTION Investigating the binding site of six novel curcumin-based diazepine compounds as a non-competitive antagonist on ionotropic, AMPA-type glutamate receptors, including homomeric and heteromeric subunits. These receptors play a pivotal role in neurodegenerative diseases such… read more here.
Keywords: binding site; non competitive; biophysical gating; curcumin based ... See more keywords