CBMG, a novel derivative of mansonone G suppresses adipocyte differentiation via suppression of PPARγ activity.
Sign Up to like & getrecommendations! Published in 2017 at "Chemico-biological interactions"
DOI: 10.1016/j.cbi.2017.06.017
Abstract: Mansorins and mansonones have been isolated from Mansonia gagei heartwoods, a traditional herbal medicine used to treat heart failure, and characterized to have anti-oxidant, anti-bacterial, anti-tumor, and anti-estrogenic activities. However, there is as yet no… read more here.
Keywords: novel derivative; adipocyte differentiation; adipogenesis; differentiation ... See more keywords
Plasma pharmacokinetics of isorhapontigenin, a novel derivative of stilbenes, in mice by LC-MS/MS method
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Asian Natural Products Research"
DOI: 10.1080/10286020.2018.1540602
Abstract: Abstract Isorhapontigenin (ISO), a novel derivative of stilbene compound, possessess good pharmacological activities such as antiviral, antioxidant, and anticancer. The purpose of this study is to investigate the pharmacokinetic of ISO in mice plasma, after… read more here.
Keywords: novel derivative; pharmacokinetics isorhapontigenin; iso; derivative stilbenes ... See more keywords
Quantification of 1D, a novel derivative of curcumin with potential antitumor activity, in rat plasma by liquid chromatography-tandem mass spectrometry: application to a pharmacokinetic study in rats
Sign Up to like & getrecommendations! Published in 2019 at "Pharmaceutical Biology"
DOI: 10.1080/13880209.2019.1603243
Abstract: Abstract Context: 1 D is a novel derivative of curcumin and shows very promising antitumor activities in various cancer cell lines. Objective: To characterize its preclinical pharmacokinetic profiles, a novel liquid chromatography-tandem mass spectrometry (LC-MS/MS) method… read more here.
Keywords: novel derivative; derivative curcumin; chromatography tandem; mass spectrometry ... See more keywords