Concentration-QT Modeling of the Novel DHFR Inhibitor P218 in Healthy Male Volunteers.
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DOI: 10.1111/bcp.14933
Abstract: AIM Given the increasing emergence of drug resistance in Plasmodium, new antimalarials are urgently required. P218 is an aminopyridine that inhibits dihydrofolate reductase being developed as a malaria chemoprotective drug. Assessing the effect of new… read more here.
Keywords: p218; novel dhfr; modeling novel; drug ... See more keywords