A novel diagnostic model based on lncRNA PTPRE expression, neutrophil count and red blood cell distribution width for diagnosis of seronegative rheumatoid arthritis
Sign Up to like & getrecommendations! Published in 2024 at "Clinical and Experimental Medicine"
DOI: 10.1007/s10238-024-01343-x
Abstract: Diagnosis of seronegative rheumatoid arthritis (SNRA) is difficult due to the lack of diagnostic markers. The study aims to construct a novel diagnostic model based on long noncoding RNAs (lncRNAs) expression and laboratory indicators to… read more here.
Keywords: diagnosis; novel diagnostic; model based; model ... See more keywords
Opportunities for novel diagnostic and cell-based therapies for Hirschsprung disease.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of pediatric surgery"
DOI: 10.1016/j.jpedsurg.2021.10.049
Abstract: Despite significant progress in our understanding of the etiology and pathophysiology of Hirschsprung disease (HSCR), early and accurate diagnosis and operative management can be challenging. Moreover, long-term morbidity following surgery, including fecal incontinence, constipation, and… read more here.
Keywords: diagnostic cell; cell based; opportunities novel; disease ... See more keywords
NFATc2-rearranged sarcomas: clinicopathologic, molecular, and cytogenetic study of 7 cases with evidence of AGGRECAN as a novel diagnostic marker
Sign Up to like & getrecommendations! Published in 2020 at "Modern Pathology"
DOI: 10.1038/s41379-020-0542-z
Abstract: NFATc2-rearranged sarcomas (NFATc2-Sarcomas) are infrequent round cell tumors characterized by EWSR1-NFATc2 fusions and FUS-NFATc2 fusions. Although our knowledge on these neoplasms has increased recently, novel diagnostic tools and more comprehensive series are still needed. Here,… read more here.
Keywords: ewsr1 nfatc2; novel diagnostic; nfatc2 rearranged; study ... See more keywords
Identification of novel diagnostic and prognostic microRNAs in sarcoma on TCGA dataset: bioinformatics and machine learning approach
Sign Up to like & getrecommendations! Published in 2025 at "Scientific Reports"
DOI: 10.1038/s41598-025-91007-x
Abstract: The discovery of unique microRNA (miR) patterns and their corresponding genes in sarcoma patients indicates their involvement in cancer development and suggests their potential use in medical management. MiRs were identified from The Cancer Genome… read more here.
Keywords: tcga dataset; novel diagnostic; identification novel; diagnostic prognostic ... See more keywords
Wilson Disease: Novel Diagnostic and Therapeutic Approaches
Sign Up to like & getrecommendations! Published in 2024 at "Seminars in Liver Disease"
DOI: 10.1055/a-2460-8999
Abstract: Abstract The Wilson disease (WD) research field is rapidly evolving, and new diagnostic and therapeutical approaches are expected to be change-gamers in the disease for the incoming years, after decades of slow changing options. Non–ceruloplasmin-bound… read more here.
Keywords: disease; novel diagnostic; diagnostic therapeutic; disease novel ... See more keywords
Circular RNAs: novel diagnostic and therapeutic targets for ischemic stroke
Sign Up to like & getrecommendations! Published in 2020 at "Expert Review of Molecular Diagnostics"
DOI: 10.1080/14737159.2020.1826313
Abstract: ABSTRACT Introduction Ischemic stroke is a life-threatening condition worldwide, including China. Nowadays, intravenous thrombolysis and mechanical thrombectomy are chiefly applied as clinical therapeutics; however, strict time windows and underlying risks limit their benefits for patients.… read more here.
Keywords: ischemic stroke; circular rnas; novel diagnostic; therapeutic targets ... See more keywords
microRNAs as Novel Diagnostic Biomarkers in Endometriosis Patients: A systematic review and meta-analysis.
Sign Up to like & getrecommendations! Published in 2021 at "Expert review of molecular diagnostics"
DOI: 10.1080/14737159.2021.1960508
Abstract: OBJECTIVE To investigate whether miRNAs have a remarkable pooled diagnostic accuracy, sensitivity and specificity as non-invasive biomarkers to distinguish endometriosis patients from non-endometriosis women. METHODS A comprehensive literature search of PubMed, Embase and ProQuest was… read more here.
Keywords: micrornas novel; analysis; novel diagnostic; review ... See more keywords
PA05 Two babies with self-improving collodion ichthyosis with ALOX12B mutations demonstrating novel diagnostic clinical signs
Sign Up to like & getrecommendations! Published in 2025 at "British Journal of Dermatology"
DOI: 10.1093/bjd/ljaf085.364
Abstract: Baby C was born at 36 + 4 weeks by spontaneous vaginal delivery and was transferred to Oxford on day two of life. On examination she had a yellow parchment-like collodion with hyperkeratotic plaques over… read more here.
Keywords: ichthyosis; collodion; novel diagnostic; alox12b mutations ... See more keywords
Eight novel diagnostic markers differentiate lineages of the highly invasive myrtle rust pathogen Austropuccinia psidii.
Sign Up to like & getrecommendations! Published in 2024 at "Plant disease"
DOI: 10.1094/pdis-10-24-2111-sr
Abstract: Austropuccinia psidii is the causal agent of myrtle rust in over 480 species within the family Myrtaceae. Lineages of A. psidii are structured by their hosts in the native range, and some have success in… read more here.
Keywords: novel diagnostic; lineage; myrtle rust; markers differentiate ... See more keywords
Is a novel diagnostic pathway for cardiology outpatient clinics in Singapore lower cost than existing practice: a cost modelling study
Sign Up to like & getrecommendations! Published in 2022 at "BMJ Open"
DOI: 10.1136/bmjopen-2021-050553
Abstract: Objective To evaluate the potential for change to costs from a decision to adopt a novel diagnostic pathway for referrals to cardiology outpatients with symptoms of chest pain. Design Costs modelling study using existing observational… read more here.
Keywords: novel diagnostic; diagnostic pathway; practice; modelling study ... See more keywords
1140 A Novel Diagnostic Prescreen to Detect Potential Intracranial Aneurysm From Circulating Blood MRNA
Sign Up to like & getrecommendations! Published in 2025 at "Neurosurgery"
DOI: 10.1227/neu.0000000000003360_1140
Abstract: INTRODUCTION: Recently our research group along with Neurovascular Diagnostics, Inc. created a PCR-based intracranial aneurysm (IA) diagnostic, called AneuScreenTM, which analyzes a 50-gene panel in whole blood to predict lesion presence. METHODS: We collected blood… read more here.
Keywords: novel diagnostic; prescreen; intracranial aneurysm; blood ... See more keywords