Novel Diarylthioether Compounds as Agents for the Treatment of Chagas Disease.
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DOI: 10.1021/acs.jmedchem.2c01725
Abstract: Herein, we describe the hit optimization of a novel diarylthioether chemical class found to be active against Trypanosoma cruzi; the parasite responsible for Chagas disease. The hit compound was discovered through a whole-cell phenotypic screen… read more here.
Keywords: diarylthioether compounds; novel diarylthioether; chagas disease; chagas ... See more keywords