Structure of a Novel Dimeric SET Domain Methyltransferase that Regulates Cell Motility.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of molecular biology"
DOI: 10.1016/j.jmb.2018.08.017
Abstract: Lysine methyltransferases (KMTs) were initially associated with transcriptional control through their methylation of histones and other nuclear proteins, but have since been found to regulate many other cellular activities. The apical complex lysine (K) methyltransferase… read more here.
Keywords: novel dimeric; structure novel; methyltransferase; motility ... See more keywords
Sceletorines A and B, two minor novel dimeric alkaloids of Mesembryanthemum tortuosum (synonym Sceletium tortuosum)
Sign Up to like & getrecommendations! Published in 2019 at "Phytochemistry Letters"
DOI: 10.1016/j.phytol.2019.03.013
Abstract: Abstract Sceletorines A and B, two unique alkaloids, were isolated for the first time from the aerial parts of Mesembryanthemum tortuosum. Their structures were determined by the extensive spectroscopic methods and their absolute configuration was… read more here.
Keywords: minor novel; dimeric alkaloids; novel dimeric; mesembryanthemum tortuosum ... See more keywords
A novel dimeric dipeptide mimetic of the BDNF selectively activates the MAPK-Erk signaling pathway
Sign Up to like & getrecommendations! Published in 2017 at "Doklady Biochemistry and Biophysics"
DOI: 10.1134/s1607672917050027
Abstract: On the basis of the structure of beta-turn of loop 2 of brain-derived neurotrophic factor (BDNF), its new dimeric dipeptide mimetic bis-(N-hexanoyl-L-seryl-L-lysine) hexamethylenediamide (GTS-201) was created. It activated TrkB and Erk, did not activate Akt,… read more here.
Keywords: novel dimeric; dimeric dipeptide; erk; dipeptide mimetic ... See more keywords