Development of novel dipeptide nitriles as inhibitors of rhodesain of Trypanosoma brucei rhodesiense.
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DOI: 10.1016/j.ejmech.2022.114328
Abstract: In this paper, we developed a new series of dipeptide nitriles that were demonstrated to be reversible rhodesain inhibitors at nanomolar level, with EC50 values against cultured T. b. brucei in the micromolar range. We also… read more here.
Keywords: development novel; dipeptide nitriles; dipeptide; novel dipeptide ... See more keywords