Porcupine Inhibitors: Novel and Emerging Anti-cancer Therapeutics Targeting the Wnt Signaling Pathway.
Sign Up to like & getrecommendations! Published in 2021 at "Pharmacological research"
DOI: 10.1016/j.phrs.2021.105532
Abstract: Porcupine is a constituent of the 19 membered Wnt family with diverse biological features such as cell differentiation, cell proliferation, cell migration, apoptosis, etc. Porcupine is a membrane-bound o-acyltransferase family protein that modulates Wnt protein… read more here.
Keywords: porcupine; porcupine inhibitors; inhibitors novel; emerging anti ... See more keywords
Novel and emerging targets for cholangiocarcinoma progression: therapeutic implications
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DOI: 10.1080/14728222.2022.2029412
Abstract: ABSTRACT Introduction Cholangiocarcinoma (CCA) is a heterogeneous group of aggressive biliary malignancies. While surgery and liver transplantation are the only potentially curative modalities for early-stage disease, limited options are available for most patients with incurable-stage… read more here.
Keywords: novel emerging; targets cholangiocarcinoma; cholangiocarcinoma progression; progression therapeutic ... See more keywords
Novel and emerging treatment strategies for lupus nephritis
Sign Up to like & getrecommendations! Published in 2022 at "Expert Review of Clinical Pharmacology"
DOI: 10.1080/17512433.2022.2138340
Abstract: ABSTRACT Introduction Lupus nephritis (LN) is a key predictor for kidney failure and death in patients with systemic lupus erythematosus. While conventional immunosuppressive treatments have improved the outcome of LN, novel therapies continue to emerge.… read more here.
Keywords: treatment strategies; strategies lupus; novel emerging; pharmacology ... See more keywords