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Published in 2018 at "European Polymer Journal"
DOI: 10.1016/j.eurpolymj.2018.01.026
Abstract: Abstract A novel 3-trifluoromethyl phenylhydroquinone epoxy monomer (3-TFMEP) and a novel 4-trifluoromethyl phenylbenzimidazole (4-TFMBI) curing agent both with trifluoromethyl moieties were synthesized via a multi-step procedure. Their chemical structures were confirmed by FT-IR and 1H…
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Keywords:
epoxy resins;
novel fluorinated;
tfmbi;
trifluoromethyl phenylbenzimidazole ... See more keywords
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Published in 2017 at "Chemical communications"
DOI: 10.1039/c6cc08900c
Abstract: Novel fluorinated ligands for gold nanoparticle labelling have been designed and synthesised. Several types of gold nanoparticles have been prepared in the presence of these fluorinated ligands alone, or in combination with non-fluorinated ligands. Their…
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Keywords:
nanoparticle labelling;
fluorinated ligands;
19f mri;
novel fluorinated ... See more keywords
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Published in 2018 at "Oncotarget"
DOI: 10.18632/oncotarget.25508
Abstract: Human carbonic anhydrase (CA) IX has emerged as a promising anticancer target and a diagnostic biomarker for solid hypoxic tumors. Novel fluorinated CA IX inhibitors exhibited up to 50 pM affinity towards the recombinant human…
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Keywords:
carbonic anhydrase;
acidification;
novel fluorinated;
clonogenic survival ... See more keywords
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Published in 2018 at "Anti-cancer agents in medicinal chemistry"
DOI: 10.2174/1871520617666170719150834
Abstract: BACKGROUND Hypoxia renders tumor cells refractory to treatment. One way to overcome this problem is the design of drug delivery systems that contain the antitumor agent within an oxygen supply medium. OBJECTIVE to evaluate whether…
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Keywords:
medium;
tumor cells;
fluorinated porphyrins;
novel fluorinated ... See more keywords
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Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24119200
Abstract: The impact of innovative technologies on the target discovery has been employed here to characterize the interactome of STIRUR 41, a promising 3-fluoro-phenyl-5-pyrazolyl-urea derivative endowed with anti-cancer activity, on neuroblastoma-related cells. A drug affinity responsive…
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Keywords:
urea derivative;
pyrazolyl urea;
fluorinated pyrazolyl;
targeting usp ... See more keywords