Articles with "novel fluoroquinolone" as a keyword



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Demonstrating the Protective Efficacy of the Novel Fluoroquinolone Finafloxacin against an Inhalational Exposure to Burkholderia pseudomallei

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Published in 2017 at "Antimicrobial Agents and Chemotherapy"

DOI: 10.1128/aac.00082-17

Abstract: ABSTRACT Burkholderia pseudomallei is the causative agent of melioidosis, a serious disease endemic in Southeast Asia and Northern Australia. Antibiotic treatment is lengthy and relapse often occurs. Finafloxacin is a novel fluoroquinolone with increased antibacterial… read more here.

Keywords: novel fluoroquinolone; burkholderia pseudomallei; pseudomallei; efficacy ... See more keywords
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In Vitro Activities and Spectrum of the Novel Fluoroquinolone Lascufloxacin (KRP-AM1977)

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Published in 2017 at "Antimicrobial Agents and Chemotherapy"

DOI: 10.1128/aac.00120-17

Abstract: ABSTRACT Lascufloxacin exhibited a broad spectrum of activity against various clinical isolates. Furthermore, lascufloxacin showed the most potent activity against Gram-positive bacteria among the quinolones tested and incomplete cross-resistance against existing quinolone-resistant strains. Enzymatic analysis… read more here.

Keywords: novel fluoroquinolone; lascufloxacin; spectrum novel; activities spectrum ... See more keywords