Articles with "novel fragment" as a keyword



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Targeting the IspD Enzyme in the MEP Pathway: Identification of a Novel Fragment Class

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Published in 2021 at "ChemMedChem"

DOI: 10.1002/cmdc.202100679

Abstract: The enzymes of the 2‐C‐methylerythritol‐d‐erythritol 4‐phosphate (MEP) pathway (MEP pathway or non‐mevalonate pathway) are responsible for the synthesis of universal precursors of the large and structurally diverse family of isoprenoids. This pathway is absent in… read more here.

Keywords: enzyme mep; novel fragment; mep pathway; pathway ... See more keywords