Whole transcriptome sequencing detects a large number of novel fusion transcripts in patients with AML and MDS.
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DOI: 10.1182/bloodadvances.2020003007
Abstract: Fusion transcripts are frequent genetic abnormalities in myeloid malignancies and are often the basis for risk stratification, minimal residual disease (MRD) monitoring, and targeted therapy. We comprehensively analyzed the fusion transcript landscape in 572 acute… read more here.
Keywords: aml mds; fusion transcripts; novel fusions; whole transcriptome ... See more keywords