Exome sequencing identifies novel genes underlying primary congenital glaucoma in the National Birth Defects Prevention Study
Sign Up to like & getrecommendations! Published in 2024 at "Birth Defects Research"
DOI: 10.1002/bdr2.2384
Abstract: Primary congenital glaucoma (PCG) affects approximately 1 in 10,000 live born infants in the United States (U.S.). PCG has a autosomal recessive inheritance pattern, and variable expressivity and reduced penetrance have been reported. Likely causal… read more here.
Keywords: birth defects; primary congenital; exome sequencing; novel genes ... See more keywords
Novel Genes Associated With Working Memory Are Identified by Combining Connectome, Transcriptome, and Genome
Sign Up to like & getrecommendations! Published in 2025 at "Human Brain Mapping"
DOI: 10.1002/hbm.70114
Abstract: Working memory (WM) plays a crucial role in human cognition. Previous candidate and genome‐wide association studies have reported many genetic variations associated with WM. However, little research has examined genetic basis of WM by using… read more here.
Keywords: transcriptome genome; working memory; genome; connectome transcriptome ... See more keywords
Identification of novel genes in testicular cancer microenvironment based on ESTIMATE algorithm‐derived immune scores
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.29898
Abstract: Testicular cancer is the most common solid malignancy among young men. We downloaded data of testicular cancer patients from The Cancer Genome Atlas database to find novel genes in the testicular cancer microenviroment based on… read more here.
Keywords: testicular cancer; based estimate; novel genes; genes testicular ... See more keywords
Novel genes in response to varying water deficit in oil crop Camelina sativa
Sign Up to like & getrecommendations! Published in 2019 at "Euphytica"
DOI: 10.1007/s10681-019-2402-9
Abstract: Camelina [Camelina sativa (L.) Crtz.] of the Brassicaceae family is an annual oilseed crop that has received increasing attention as a biofuel feedstock because of its excellent adaptability to low fertility drylands. Even though moisture… read more here.
Keywords: camelina; water; water deficit; novel genes ... See more keywords
Comparative morphological, physiological, biochemical and genomic studies reveal novel genes of Dunaliella bioculata and D. quartolecta in response to salt stress.
Sign Up to like & getrecommendations! Published in 2021 at "Molecular biology reports"
DOI: 10.1007/s11033-021-06984-9
Abstract: BACKGROUND Salinity is an essential abiotic stress in plants. Dunaliella is a genus of high-salt-tolerant microalgae. The present study aimed to compare the characterizations of D. bioculata and D. quartolecta at different levels and investigate… read more here.
Keywords: salt; response salt; novel genes; salt stress ... See more keywords
Identifying novel genes for carcass traits by testing G × E interaction through genome-wide meta-analysis in Chinese Simmental beef cattle
Sign Up to like & getrecommendations! Published in 2018 at "Livestock Science"
DOI: 10.1016/j.livsci.2018.04.001
Abstract: Abstract Over the past decade, genome-wide association studies (GWASs) have successfully identified hundreds of genetic variants associated with economically important production traits in beef cattle. Environmental factors, such as farm, year, and season, have been… read more here.
Keywords: genome wide; chinese simmental; beef cattle; novel genes ... See more keywords
Identification of novel genes associated with duck OASL in response to influenza A virus
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Integrative Agriculture"
DOI: 10.1016/s2095-3119(19)62685-7
Abstract: Abstract 2´-5´-Oligoadenylate synthetase like protein (OASL) plays a key role in response to viral infections through selectively activating the OAS/RNase L or OASL/RIG-I signaling pathway. Although classic pathway of OASL is well-known, its regulated genes… read more here.
Keywords: protein; response; novel genes; identification novel ... See more keywords
De Novo Assembly of 20 Chicken Genomes Reveals the Undetectable Phenomenon for Thousands of Core Genes on Microchromosomes and Subtelomeric Regions
Sign Up to like & getrecommendations! Published in 2022 at "Molecular Biology and Evolution"
DOI: 10.1093/molbev/msac066
Abstract: Abstract The gene numbers and evolutionary rates of birds were assumed to be much lower than those of mammals, which is in sharp contrast to the huge species number and morphological diversity of birds. It… read more here.
Keywords: subtelomeric regions; novo assembly; assembly chicken; novel genes ... See more keywords
Impact of Natural Transformation on the Acquisition of Novel Genes in Bacteria
Sign Up to like & getrecommendations! Published in 2025 at "Molecular Biology and Evolution"
DOI: 10.1093/molbev/msaf192
Abstract: Natural transformation is the only process of gene exchange under the exclusive control of the recipient bacteria. It has often been considered as a source of novel genes but quantitative assessments of this claim are… read more here.
Keywords: gene acquisition; acquisition; novel genes; transformation ... See more keywords
Novel Genes Potentially Involved in Fibroblasts of Diabetic Wound
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Diabetes Research"
DOI: 10.1155/2021/7619610
Abstract: Fibroblasts are the essential cell type of skin, highly involved in the wound regeneration process. In this study, we sought to screen out the novel genes which act important roles in diabetic fibroblasts through bioinformatic… read more here.
Keywords: involved fibroblasts; potentially involved; fibroblasts diabetic; diabetic wound ... See more keywords
An integrated method for the identification of novel genes related to oral cancer
Sign Up to like & getrecommendations! Published in 2017 at "PLoS ONE"
DOI: 10.1371/journal.pone.0175185
Abstract: Cancer is a significant public health problem worldwide. Complete identification of genes related to one type of cancer facilitates earlier diagnosis and effective treatments. In this study, two widely used algorithms, the random walk with… read more here.
Keywords: rwr based; oral cancer; novel genes; genes related ... See more keywords