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Novel GluN2B-Selective NMDA Receptor Negative Allosteric Modulator Possesses Intrinsic Analgesic Properties and Enhances Analgesia of Morphine in a Rodent Tail Flick Pain Model

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Published in 2023 at "ACS Chemical Neuroscience"

DOI: 10.1021/acschemneuro.2c00779

Abstract: Many cases of accidental death associated with drug overdose are due to chronic opioid use, tolerance, and addiction. Analgesic tolerance is characterized by a decreased response to the analgesic effects of opioids, requiring increasingly higher… read more here.

Keywords: allosteric modulator; glun2b selective; novel glun2b; eu93 108 ... See more keywords