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Published in 2020 at "Clinical Drug Investigation"
DOI: 10.1007/s40261-020-00981-9
Abstract: Background and Objectives Matrix metalloproteinases (MMPs) are proteases with different biological and pathological activities, and many have been linked to several diseases. Targeting individual MMPs may offer a safer therapeutic potential for several diseases. We…
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Keywords:
highly selective;
safety tolerability;
capsule;
study ... See more keywords
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Published in 2021 at "Journal of The Taiwan Institute of Chemical Engineers"
DOI: 10.1016/j.jtice.2021.02.008
Abstract: Abstract Herein, the synthesis of a novel highly-oxidized carbon nanotubes (OMWCNT) modified by the Emeraldine salt (ES)-based polyaniline (PANI) nanofibers (NFs) was carried out. The zinc doped OMWCNT-PANI particles were synthesized to achieve novel nanoparticles,…
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Keywords:
pani;
pani nanofibers;
carbon nanotubes;
nano composite ... See more keywords
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Published in 2020 at "Journal of Molecular Structure"
DOI: 10.1016/j.molstruc.2019.126990
Abstract: Abstract A new N-acylhydrazone based on acridone (S1) was synthesized by Schiff base condensation of 2-(9-oxoacridin-10-yl)acetohydrazide and salicylaldehyde and studied as selective fluorescence turn-off sensing towards Cu2+ ions in aqueous media. S1 demonstrated fluorescence turn-off…
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Keywords:
detection;
fluorescence;
novel highly;
towards cu2 ... See more keywords
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Published in 2017 at "Neuropharmacology"
DOI: 10.1016/j.neuropharm.2016.10.019
Abstract: Background and purpose: Since GABAergic dysfunction underlies a variety of neurological and psychiatric disorders, numerous strategies leading to the augmentation of GABAergic neurotransmission have been introduced. One of them is the inhibition of GABA reuptake…
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Keywords:
highly potent;
ddpm 2571;
inhibitor;
antidepressant ... See more keywords
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Published in 2018 at "Separation and Purification Technology"
DOI: 10.1016/j.seppur.2017.08.008
Abstract: Abstract Only 3–5% of the UV photon flux reaching the earth’s surface, therefore it would be hugely beneficial to extend the light absorption of CeO2 to the visible light region. The present work is focused…
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Keywords:
ceo2 nanostructures;
visible light;
novel highly;
ceo2 ... See more keywords
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Published in 2022 at "Journal of medicinal chemistry"
DOI: 10.1021/acs.jmedchem.2c00834
Abstract: Renin is the rate-limiting enzyme in the renin-angiotensin-aldosterone system (RAAS) which regulates blood pressure and renal function and hence is an attractive target for the treatment of hypertension and cardiovascular/renal diseases. However, the development of…
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Keywords:
highly potent;
direct renin;
novel highly;
discovery sph3127 ... See more keywords
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Published in 2018 at "ACS Sustainable Chemistry & Engineering"
DOI: 10.1021/acssuschemeng.8b00908
Abstract: A novel and highly active photocatalytic material, self-doped potassium niobate composite microflowers stimulated by noble-metal-free copper nanoparticles (Cu/K4Nb6O17), was achieved. The composition and structure of the composite microflowers were characterized by X-ray diffraction (XRD), high…
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Keywords:
hydrogen;
potassium niobate;
composite microflowers;
novel highly ... See more keywords
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Published in 2021 at "Organic Chemistry Frontiers"
DOI: 10.1039/d1qo00793a
Abstract: A novel tribromination method to prepare versatile intermediate 1,1,2-tribromoethyl arenes, which can not only be transformed to synthetically valuable 1-bromoalkynes via elimination but also be hydrolyzed to a variety of α-bromoketones, was developed.
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Keywords:
tribromoethyl arenes;
novel highly;
arenes novel;
efficient precursors ... See more keywords
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Published in 2017 at "Cancer Research"
DOI: 10.1158/1538-7445.am2017-1181
Abstract: Over the past decade, protein ubiquitination has emerged as an important post-translational modification with regulatory functions in all important cellular processes. Deubiquitinating enzymes (DUBs) including ubiquitin specific proteases (USPs) are cysteine proteases that catalyse the…
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Keywords:
highly potent;
potent selective;
discovery;
novel highly ... See more keywords
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Published in 2021 at "Frontiers in Medicine"
DOI: 10.3389/fmed.2021.697605
Abstract: COVID-19 pandemics has led to genetic diversification of SARS-CoV-2 and the appearance of variants with potential impact in transmissibility and viral escape from acquired immunity. We report a new and highly divergent lineage containing 21…
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Keywords:
lineage;
highly divergent;
novel highly;
spike ... See more keywords
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Published in 2023 at "Applied Sciences"
DOI: 10.3390/app13085038
Abstract: The proton conductivity and structural properties of (1–x)CsH2PO4–xZnSnO3 composites with compositions of x = 0.2–0.8 were studied. Zinc stannate ZnSnO3 was prepared by the thermal decomposition of zinc hydroxostannate ZnSn(OH)6, which was synthesized by hydrolytic…
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Keywords:
proton conductivity;
highly dispersed;
novel highly;
zinc stannate ... See more keywords