AnnoLnc: A One-Stop Portal to Systematically Annotate Novel Human Long Noncoding RNAs.
Sign Up to like & getrecommendations! Published in 2021 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-1158-6_8
Abstract: While more than a hundred thousand long noncoding RNAs (lncRNAs) have been identified in human genome, their biological functions and regulation are largely elusive. Here we present AnnoLnc, a one-stop online annotation portal for human… read more here.
Keywords: long noncoding; novel human; annolnc one; one stop ... See more keywords
A novel human tumoroid 3D model of sustained ACTH-secreting cell cultures to study critically needed therapies for Cushing's disease
Sign Up to like & getrecommendations! Published in 2021 at "EBioMedicine"
DOI: 10.1016/j.ebiom.2021.103368
Abstract: The pituitary gland is a master endocrine organ composed of distinct hormone-producing cell types that serve as sensors to integrate central and peripheral signals in order to fine-tune whole-body homeostasis and control multiple physiological functions… read more here.
Keywords: cushing disease; novel human; cell cultures; cell ... See more keywords
D05 Developing novel human isogenic cellular models for Duchenne muscular dystrophy
Sign Up to like & getrecommendations! Published in 2017 at "Neuromuscular Disorders"
DOI: 10.1016/s0960-8966(17)30234-1
Abstract: been numerous advances in the fi eld, many aspects of the pathology and disease progression over time are still unclear. Here, we have utilised high-resolution isoelectric focusing liquid chromatography-mass spectrometry (HiRIEF-LCMS/MS; using isobaric labelling with… read more here.
Keywords: protein expression; d05 developing; novel human; developing novel ... See more keywords
Uncovering novel human gut virome using ultra-deep metagenomic sequencing
Sign Up to like & getrecommendations! Published in 2022 at "Chinese Medical Journal"
DOI: 10.1097/cm9.0000000000002382
Abstract: Human gastrointestinal tract harbors trillions of commensal microbes including bacteria, viruses, and fungi to form an ecological community, commonly known as the gut microbiome. Being the second most dominant taxonomic kingdom in the gut (5.8%… read more here.
Keywords: gut; novel human; uncovering novel; gut virome ... See more keywords
Abstract 35: Development of novel human hepatocellular carcinoma models using genetically modified human hepatocytes in FSRG humanized liver mice
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Research"
DOI: 10.1158/1538-7445.am2023-35
Abstract: The incidence of liver cancer is growing worldwide, and it is estimated that by 2025, over 1 million individuals will be affected by liver cancer every year. Hepatocellular carcinoma (HCC) accounts for about 90% of… read more here.
Keywords: hepatocellular carcinoma; human hepatocytes; novel human; humanized liver ... See more keywords
Escherichia albertii, a novel human enteropathogen, colonizes rat enterocytes and translocates to extra-intestinal sites
Sign Up to like & getrecommendations! Published in 2017 at "PLoS ONE"
DOI: 10.1371/journal.pone.0171385
Abstract: Diarrhea is the second leading cause of death of children up to five years old in the developing countries. Among the etiological diarrheal agents are atypical enteropathogenic Escherichia coli (aEPEC), one of the diarrheagenic E.… read more here.
Keywords: albertii novel; novel human; enteropathogen; human enteropathogen ... See more keywords
Healing of intrabony defects using a novel human recombinant amelogenin: a preclinical study.
Sign Up to like & getrecommendations! Published in 2023 at "Quintessence international"
DOI: 10.3290/j.qi.b4007601
Abstract: OBJECTIVE To histologically evaluate the effects of a novel human recombinant amelogenin (rAmelX) on periodontal wound healing/regeneration in intrabony defects. METHOD AND MATERIALS Intrabony defects were surgically created in the mandible of 3 minipigs. Twelve… read more here.
Keywords: recombinant amelogenin; group; intrabony defects; novel human ... See more keywords
A Novel Human Brainstem Map Based on True-Color Sectioned Images
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Korean Medical Science"
DOI: 10.3346/jkms.2023.38.e76
Abstract: Background Existing atlases for the human brainstem were generated from magnetic resonance images or traditional histologically stained slides, but both are insufficient for the identification of detailed brainstem structures at uniform intervals. Methods A total… read more here.
Keywords: brainstem; sectioned images; novel human; true color ... See more keywords
Novel Human Polymorphisms Define a Key Role for the SLC26A6-STAS Domain in Protection From Ca2+-Oxalate Lithogenesis
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2020.00405
Abstract: Impaired homeostasis of the carboxylic acids oxalate and citrate, dramatically increases the risk for the formation of Ca2+-oxalate kidney stones, which is the most common form of kidney stones in humans. Renal homeostasis of oxalate… read more here.
Keywords: novel human; slc26a6 stas; citrate; stas domain ... See more keywords
Isolation of Two Novel Human Anti-CTLA-4 mAbs with Intriguing Biological Properties on Tumor and NK Cells
Sign Up to like & getrecommendations! Published in 2020 at "Cancers"
DOI: 10.3390/cancers12082204
Abstract: The cytotoxic T lymphocyte-antigen 4 (CTLA-4) has been considered an IC exclusively expressed on T cells, where it counteracts the co-stimulatory CD28 receptor, by competing for its binding to CD-80 and CD-86. We recently found… read more here.
Keywords: novel human; mabs; ctla; human mouse ... See more keywords