Novel immunotherapy combinations in clinical trials for hepatocellular carcinoma: will they shape the future treatment landscape?
Sign Up to like & getrecommendations! Published in 2022 at "Expert Opinion on Investigational Drugs"
DOI: 10.1080/13543784.2022.2072726
Abstract: ABSTRACT Introduction Underlying liver disease and the intrinsic chemoresistance have historically hampered the development of efficacious treatments in HCC. However, in the last few years, immunotherapy-based combinations have emerged as efficacious therapeutic strategy in this… read more here.
Keywords: checkpoint inhibitors; clinical trials; immunotherapy combinations; combinations clinical ... See more keywords
Novel immunotherapy combinations for genitourinary cancers
Sign Up to like & getrecommendations! Published in 2020 at "Expert Opinion on Biological Therapy"
DOI: 10.1080/14712598.2020.1713086
Abstract: ABSTRACT Introduction: Several immune checkpoint inhibitors are FDA-approved for metastatic/advanced RCC and urothelial carcinoma (UC) based on improvements in survival. The dendritic cell vaccine, sipuleucel-T, is also approved for patients with mCRPC, based on a… read more here.
Keywords: immunotherapy combinations; genitourinary cancers; novel immunotherapy; combinations genitourinary ... See more keywords
Novel immunotherapy and treatment modality for severe food allergies
Sign Up to like & getrecommendations! Published in 2017 at "Current Opinion in Allergy and Clinical Immunology"
DOI: 10.1097/aci.0000000000000365
Abstract: Purpose of review In recent years, many studies on oral immunotherapy (OIT) have been conducted; however, few have focused on severe food allergies. The purpose of this review was to assess the efficacy and safety… read more here.
Keywords: novel immunotherapy; immunotherapy treatment; food; food allergies ... See more keywords
Abstract 1107: LAG3 in Solid Tumors as a Potential Novel Immunotherapy Target
Sign Up to like & getrecommendations! Published in 2019 at "Tumor Biology"
DOI: 10.1158/1538-7445.am2019-1107
Abstract: We performed prospective immunohistochemical analysis of LAG3 for 430 consecutive patients with advanced gastrointestinal, genitourinary, or rare cancers between June 2012 and March 2016. Most patients (428/430, 99.5%) were evaluable for LAG3 expression by immunohistochemistry.… read more here.
Keywords: tumors potential; novel immunotherapy; potential novel; target ... See more keywords
Abstract 5664: A novel immunotherapy for relapsed/refractory acute lymphoblastic leukemia (ALL)
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Research"
DOI: 10.1158/1538-7445.am2023-5664
Abstract: Successful treatment of ALL has been a major feat of modern medicine. Overall, 5-year survival in pediatric ALL patients approaches 90%, but 10-15% of patients will relapse. In relapse, ALL is still challenging to cure… read more here.
Keywords: refractory acute; relapsed refractory; novel; acute lymphoblastic ... See more keywords
A novel immunotherapy of Brucellosis in cows monitored non invasively through a specific biomarker
Sign Up to like & getrecommendations! Published in 2018 at "PLoS Neglected Tropical Diseases"
DOI: 10.1371/journal.pntd.0006393
Abstract: Brucellosis is an important zoonotic disease causing huge economic losses worldwide. Currently no effective immunotherapy for Brucellosis or any biomarker to monitor the efficacy of therapy is available. Treatment is ineffective and animals remain carrier… read more here.
Keywords: novel immunotherapy; biomarker; immunotherapy brucellosis; brucellosis ... See more keywords
Novel immunotherapy strategies for hepatobiliary cancers.
Sign Up to like & getrecommendations! Published in 2018 at "Immunotherapy"
DOI: 10.2217/imt-2018-0024
Abstract: Despite recent advancements in therapeutic options for advanced hepatobiliary cancers, there remains an unmet need for innovative systemic treatments. Immunotherapy has shown an ability to provide prolonged clinical benefit, but this benefit remains limited to… read more here.
Keywords: benefit; immunotherapy strategies; novel immunotherapy; hepatobiliary cancers ... See more keywords
Targeting CD47 as a Novel Immunotherapy for Breast Cancer
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2022.924740
Abstract: Nowadays, breast cancer has become the most common cancer worldwide with a high mortality rate. Immune checkpoint blockade holds great promise in tumor‐targeted therapy, and CD47 blockade as one immune therapy is undergoing various preclinical… read more here.
Keywords: cd47 novel; targeting cd47; breast cancer; novel immunotherapy ... See more keywords
Novel immunotherapy in metastatic renal cell carcinoma
Sign Up to like & getrecommendations! Published in 2017 at "Investigative and Clinical Urology"
DOI: 10.4111/icu.2017.58.4.220
Abstract: Despite the rapid development of therapeutic modalities for metastatic renal cell carcinoma (mRCC) over the past decade to include a number of targeted antiangiogenic therapies and traditional immunotherapy, such as high-dose interleukin-2 and interferon-α, mRCC… read more here.
Keywords: renal cell; novel immunotherapy; cell carcinoma; metastatic renal ... See more keywords