Discovery of a novel multifunctional carbazole–aminoquinoline dimer for Alzheimer's disease: copper selective chelation, anti-amyloid aggregation, and neuroprotection
Sign Up to like & getrecommendations! Published in 2017 at "Medicinal Chemistry Research"
DOI: 10.1007/s00044-017-2101-9
Abstract: A novel multifunctional carbazole–aminoquinoline dimer PZ001 was designed, synthesized, and evaluated. The results indicated that PZ001 possessed selective copper chelation, and inhibited copper-induced Aβ1–42 aggregation. Furthermore, PZ001 exerted powerful neuroprotection against glutamate-induced HT22 cell death.… read more here.
Keywords: novel multifunctional; copper; multifunctional carbazole; carbazole aminoquinoline ... See more keywords
Novel multifunctional solid slippery surfaces with self-assembled fluorine-free small molecules
Sign Up to like & getrecommendations! Published in 2021 at "Chemical Engineering Journal"
DOI: 10.1016/j.cej.2020.127064
Abstract: Abstract Functional slippery surfaces have broad applications in engineering and bioengineering processes, such as water harvesting, photocatalysis, wastewater treatment and food industry. In this work, for the first time, we report the fabrication of a… read more here.
Keywords: functional slippery; water; novel multifunctional; slippery ... See more keywords
A novel multifunctional ceramic with photoluminescence and outstanding energy storage properties
Sign Up to like & getrecommendations! Published in 2020 at "Chemical Engineering Journal"
DOI: 10.1016/j.cej.2020.127368
Abstract: Abstract Recently, the energy storage density of lead-free ceramics has been improved significantly, however, the single functional material can no longer satisfy the development trend of miniaturization and integration of electronic devices, thus developing multifunctional… read more here.
Keywords: multifunctional ceramic; novel multifunctional; energy; energy storage ... See more keywords
A novel multifunctional Salecan/κ-carrageenan composite hydrogel with anti-freezing properties: Advanced rheology, thermal analysis and model fitting.
Sign Up to like & getrecommendations! Published in 2022 at "International journal of biological macromolecules"
DOI: 10.1016/j.ijbiomac.2022.03.054
Abstract: The multifunctional hydrogels (HGs) have attracted intensive concern in biomedicine, food, and flexible devices. Nevertheless, chemically crosslinked synthetic HGs are commonly under specific restrictions because of their possible biotoxicity. This study focuses on the employment… read more here.
Keywords: rheology; model fitting; novel multifunctional; salecan carrageenan ... See more keywords
MiR-375: A novel multifunctional regulator.
Sign Up to like & getrecommendations! Published in 2021 at "Life sciences"
DOI: 10.1016/j.lfs.2021.119323
Abstract: MiR-375, a primitively described beta cell-specific miRNA, is confirmed to function as multi-functional regulator in diverse typical cellular pathways according to the follow-up researches. Based on the existing studies, miR-375 can regulate many functional genes… read more here.
Keywords: novel multifunctional; mir 375; multifunctional regulator; regulator ... See more keywords
A novel multifunctional adsorbent of pomegranate peel extract and activated anthracite for Mn(VII) and Cr(VI) uptake from solutions: Experiments and theoretical treatment
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Molecular Liquids"
DOI: 10.1016/j.molliq.2020.113169
Abstract: Abstract The structure of anthracite (An) was exfoliated by H2O2 and impregnated with pomegranate peel extract (PP) to synthesize a new multifunctional (An/PP) composite. This new composite was characterized and applied for Cr(VI) and Mn(VII)… read more here.
Keywords: novel multifunctional; adsorption; peel extract; pomegranate peel ... See more keywords
A novel multifunctional electronic calibration kit integrated by MEMS SPDT switches
Sign Up to like & getrecommendations! Published in 2021 at "Chinese Physics B"
DOI: 10.1088/1674-1056/abf12b
Abstract: Design and simulation results of a novel multifunctional electronic calibration kit based on microelectromechanical system (MEMS) single-pole double-throw (SPDT) switches are presented in this paper. The short-open-load-through (SOLT) calibration states can be completed simultaneously by… read more here.
Keywords: electronic calibration; novel multifunctional; calibration; multifunctional electronic ... See more keywords
Novel multifunctional iron chelators of the aroyl nicotinoyl hydrazone class that markedly enhance cellular NAD+/NADH ratios
Sign Up to like & getrecommendations! Published in 2020 at "British Journal of Pharmacology"
DOI: 10.1111/bph.14963
Abstract: Alzheimer's disease (AD) is a multifactorial condition leading to cognitive decline and represents a major global health challenge in ageing populations. The lack of effective AD therapeutics led us to develop multifunctional nicotinoyl hydrazones to… read more here.
Keywords: iron chelators; chelators aroyl; novel multifunctional; aroyl nicotinoyl ... See more keywords
A novel multifunctional skin care formulation with a unique blend of antipollution, brightening and antiaging active complexes
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cosmetic Dermatology"
DOI: 10.1111/jocd.13176
Abstract: High demand on anti‐aging skin care encourage the improvement and development of more personalized formulations with additional benefits for general skin health and age associated skin signs. The skin aging physical and biological phenotypes manifest… read more here.
Keywords: novel multifunctional; skin care; skin; care formulation ... See more keywords
A Novel, Multifunctional, Floatable, Lightweight Cement Composite: Development and Properties
Sign Up to like & getrecommendations! Published in 2018 at "Materials"
DOI: 10.3390/ma11102043
Abstract: This paper presents the development of a novel, multifunctional, floatable, lightweight cement composite (FLCC) using three different types of glass microspheres for structural engineering applications. Eight different mixtures of FLCC were produced and their matrix-related… read more here.
Keywords: novel multifunctional; lightweight cement; multifunctional floatable; cement ... See more keywords
Novel Multifunctional Spherosilicate-Based Coupling Agents for Improved Bond Strength and Quality in Restorative Dentistry
Sign Up to like & getrecommendations! Published in 2022 at "Materials"
DOI: 10.3390/ma15103451
Abstract: The aim of this study was to investigate the restorative connections of composite materials after fracture, under controlled conditions of treating the materials with novel, spherosilicate-based (SS) primers bearing both methacryl (MA) and trimethoxysilyl (TMOS)… read more here.
Keywords: strength; quality; spherosilicate; spherosilicate based ... See more keywords