Searching for Novel Noncovalent Nuclear Export Inhibitors through a Drug Repurposing Approach.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of medicinal chemistry"
DOI: 10.1021/acs.jmedchem.2c01772
Abstract: Chromosomal region maintenance protein 1 (CRM1) is a validated anticancer drug target, and its covalent inhibitor KPT-330 has been approved for marketing. However, the development of CRM1 inhibitors, especially the noncovalent ones, is still very… read more here.
Keywords: novel noncovalent; searching novel; drug repurposing; nuclear export ... See more keywords