Abstract 3870: Validation of a canine intestinal organoid model as a preclinical screen to assess GI toxicity in novel oncology drug development
Sign Up to like & getrecommendations! Published in 2018 at "Cancer Research"
DOI: 10.1158/1538-7445.am2018-3870
Abstract: Gastrointestinal (GI) toxicity is a common and often severe dose-limiting side effect of chemotherapy. Symptoms include diarrhea, dehydration and ulceration leading to increased susceptibility to infection, due in part to the damage or loss of… read more here.
Keywords: toxicity; organoid model; novel oncology; intestinal organoid ... See more keywords
Do elderly and young patients derive similar relative survival benefits from novel oncology drugs? A systematic review and meta-analysis.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2017.35.15_suppl.10029
Abstract: 10029Background: Elderly patients are commonly believed to derive less benefit from cancer drugs, even if they fulfil clinical trial eligibility. We aim to examine if novel oncology drugs provide d... read more here.
Keywords: patients derive; young patients; oncology drugs; elderly young ... See more keywords