Novel oral anticoagulants (NOACs) in patients with atrial fibrillation (AF) and diabetes—Good or excellent?
Sign Up to like & getrecommendations! Published in 2017 at "Diabetes/Metabolism Research and Reviews"
DOI: 10.1002/dmrr.2893
Abstract: Atrial fibrillation (AF) is associated with an increased risk of stroke, systemic embolism, and death. In the last decade, novel oral anticoagulants (NOACs) have emerged and are nowadays a key player in the anticoagulant armamentarium… read more here.
Keywords: atrial fibrillation; oral anticoagulants; anticoagulants noacs; novel oral ... See more keywords
Safety, Tolerability and Pharmacokinetics of Yimitasvir Phosphate Capsule, a Novel Oral Hepatitis C Virus NS5A Inhibitor, in Healthy Chinese Volunteers
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DOI: 10.1007/s40261-019-00791-8
Abstract: Background and ObjectivesYimitasvir is a novel oral hepatitis C virus non-structural protein 5A (NS5A) inhibitor. The aims of this first-in-human study were to evaluate the safety, tolerability and pharmacokinetics of single and multiple doses of… read more here.
Keywords: oral hepatitis; ns5a inhibitor; safety tolerability; novel oral ... See more keywords
Efficacy and safety of novel oral anticoagulants versus low molecular weight heparin in cancer patients with venous thromboembolism: A systematic review and meta-analysis.
Sign Up to like & getrecommendations! Published in 2020 at "Critical reviews in oncology/hematology"
DOI: 10.1016/j.critrevonc.2020.103074
Abstract: Novel Oral Anticoagulants (NOACs) have been considered for treating cancer-related venous thromboembolism (VTE), but safety issues have been raised. We performed a systematic review and pairwise meta-analysis of the efficacy and safety of NOACs versus… read more here.
Keywords: oral anticoagulants; systematic review; safety; novel oral ... See more keywords
Novel oral anticoagulant induced upper limb haematoma: A case report
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DOI: 10.1016/j.jpra.2017.08.008
Abstract: The development of novel oral anticoagulant agents (NOACs) such as dabigatran, rivaroxaban, apixaban and edoxaban has given patients better treatment alternatives to aspirin, clopidogrel, heparin and warfarin, mainly for stroke prophylaxis in patients with non-valvular… read more here.
Keywords: limb; oral anticoagulant; case; novel oral ... See more keywords
Safety of Novel Oral Anticoagulants After Catheter‐Directed Thrombolysis in Patients With Venous Thromboembolism: IP275.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Vascular Surgery"
DOI: 10.1016/j.jvs.2018.03.222
Abstract: Objective: The emergence of novel oral anticoagulant agents (NOACs) has increased the ability of physicians to provide patients with reliable anticoagulation (AC) therapy for venous thromboembolism (VTE). Their effectiveness in comparison to vitamin K antagonists… read more here.
Keywords: vte; catheter; tpa; safety ... See more keywords
Comparison of Anticoagulant Therapy for Atrial Fibrillation - Novel Oral Anticoagulants Versus Vitamin K Antagonists.
Sign Up to like & getrecommendations! Published in 2018 at "Progress in cardiovascular diseases"
DOI: 10.1016/j.pcad.2018.01.005
Abstract: In patients with non-valvular atrial fibrillation (NVAF), oral anticoagulation is important for prevention of stroke and systemic embolism (SE). While Vitamin K antagonists (VKAs) have historically been the standard of care, these medications are limited… read more here.
Keywords: atrial fibrillation; oral anticoagulants; comparison anticoagulant; novel oral ... See more keywords
Novel Oral Anticoagulants in Patients Undergoing Cranial Surgery.
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DOI: 10.1016/j.wneu.2017.06.105
Abstract: BACKGROUND The number of patients treated with novel oral anticoagulants (NOACs) is increasing. Despite growing clinical relevance, guidelines on the perioperative management of neurosurgical patients treated with NOACs are still lacking. The aim of this… read more here.
Keywords: oral anticoagulants; cranial surgery; patients undergoing; novel oral ... See more keywords
NOVEL ORAL ANTICOAGULANTS ARE SAFE AND EFFECTIVE FOR THROMBOEMBOLIC PROPHYLAXIS IN OBESE PATIENTS WITH ATRIAL FIBRILLATION
Sign Up to like & getrecommendations! Published in 2020 at "Journal of the American College of Cardiology"
DOI: 10.1016/s0735-1097(20)31132-3
Abstract: The prevalence of obesity in U.S. adults is 38% and class III obesity (BMI ≥40 kg/m2) approaches 8%, many have comorbid atrial fibrillation (AF). Recent recommendations caution against novel oral anticoagulant (NOAC) use for thromboembolic… read more here.
Keywords: atrial fibrillation; novel oral; obese patients; thromboembolic prophylaxis ... See more keywords
UNINTERRUPTED VS. INTERRUPTED NOVEL ORAL ANTICOAGULANT (NOAC) DOSING STRATEGY BEFORE CATHETER ABLATION OF ATRIAL FIBRILLATION: A METANALYSIS OF RANDOMIZED CONTROLLED TRIALS FOR PERIPROCEDURAL COMPLICATIONS
Sign Up to like & getrecommendations! Published in 2020 at "Journal of the American College of Cardiology"
DOI: 10.1016/s0735-1097(20)31150-5
Abstract: In catheter ablation of atrial fibrillation (PVI) anticoagulation with novel oral anticoagulants (NOAC) is superior. However both interrupted and uninterrupted doses are used. However, studies comparing this minimally interrupted strategy (IAC) with uninterrupted (UAC) strategy… read more here.
Keywords: atrial fibrillation; ablation atrial; novel oral; catheter ablation ... See more keywords
Development of a novel oral complex lipid emulsion containing triptolide for targeting pancreatic cancer
Sign Up to like & getrecommendations! Published in 2022 at "Pharmaceutical Development and Technology"
DOI: 10.1080/10837450.2022.2127767
Abstract: Abstract Triptolide (TP), a diterpenoid triepoxide, exhibits strong anti-cancer activities, especially against pancreatic cancer, but its clinical application is limited by organ toxicity. TP was combined with diammonium glycyrrhizinate (DG), as a cytoprotective agent, in… read more here.
Keywords: cancer; pancreatic cancer; oral complex; complex lipid ... See more keywords
437 Efficacy of a novel oral appliance and the influence of OSA pathophysiological traits on treatment response
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DOI: 10.1093/sleep/zsab072.436
Abstract: Oral appliance therapy is a recommended alternative to CPAP for OSA. Approximately 50% of patients have a major reduction in OSA severity but successful treatment outcome remains challenging to predict. Previous prediction methods have focused… read more here.
Keywords: therapy; pathophysiological traits; treatment; appliance ... See more keywords