Development of a Platform To Enable Efficient Permeability Evaluation of Novel Organo-Peptide Macrocycles.
Sign Up to like & getrecommendations! Published in 2019 at "ACS medicinal chemistry letters"
DOI: 10.1021/acsmedchemlett.9b00036
Abstract: As more macrocycle structures are utilized to drug intracellular targets, new platforms are needed to facilitate the discovery of cell permeable compounds in this unique chemical space. Herein, a method is disclosed that allows for… read more here.
Keywords: permeability evaluation; novel organo; organo peptide; evaluation novel ... See more keywords
Converting p-terphenyl into a novel organo-catalyst for LED-driven energy and electron transfer photoreactions in water.
Sign Up to like & getrecommendations! Published in 2021 at "Chemical communications"
DOI: 10.1039/d1cc01947c
Abstract: p-Terphenyl is a potent photoredox catalyst under UV-irradiation. Aiming for more sustainable reaction conditions, we added two sulfonate groups to this key structure to achieve water solubility and incorporated an SO2-bridge thereby shifting the absorption… read more here.
Keywords: organo catalyst; water; terphenyl novel; converting terphenyl ... See more keywords