Synthesis of Novel Pentacyclic Triterpenoid Derivatives that Induce Apoptosis in Cancer Cells through a ROS-dependent, Mitochondrial-Mediated Pathway.
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DOI: 10.1021/acs.molpharmaceut.2c00885
Abstract: Betulinic acid (BA) and oleanolic acid (OA) are plant-derived conjugates found in various medicinal plants that have emerged as potential antitumor agents. Herein, a series of novel BA and OA derivatives were synthesized by conjugation… read more here.
Keywords: cancer cells; apoptosis; novel pentacyclic; triterpenoid derivatives ... See more keywords