Two/three-dimensional interfacial properties of the novel peptide as a selective destroyer of biomembrane
Sign Up to like & getrecommendations! Published in 2019 at "Colloids and Surfaces A: Physicochemical and Engineering Aspects"
DOI: 10.1016/j.colsurfa.2019.04.023
Abstract: Abstract Peptides are widely used in biomedicine field for their good biocompatibility and variable secondary structures. In this study, a novel amphiphilic peptide (amPE) was designed for antimicrobial agent. Its thermal responsiveness in solution and… read more here.
Keywords: dimensional interfacial; properties novel; novel peptide; interfacial properties ... See more keywords
A novel peptide-based sensor platform for detection of anti-Toxoplasma gondii immunoglobulins.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of pharmaceutical and biomedical analysis"
DOI: 10.1016/j.jpba.2019.112778
Abstract: Toxoplasma gondii is an intracellular protozoan parasite responsible for toxoplasmosis, which affects humans and animals. Serologic detection of anti-T. gondii immunoglobulins plays a crucial role in the clinical diagnosis of toxoplasmosis. In this work, a… read more here.
Keywords: novel peptide; gondii; gondii immunoglobulins; detection anti ... See more keywords
Design and Evaluation of a Novel Peptide–Drug Conjugate Covalently Targeting SARS-CoV-2 Papain-like Protease
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Medicinal Chemistry"
DOI: 10.1021/acs.jmedchem.1c02022
Abstract: Coronavirus disease 2019 (COVID-19) pandemic, a global health threat, was caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The SARS-CoV-2 papain-like cysteine protease (PLpro) was recognized as a promising drug target because of multiple… read more here.
Keywords: sars cov; drug; cov papain; novel peptide ... See more keywords
A novel peptide targeting gastrin releasing peptide receptor for pancreatic neoplasm detection.
Sign Up to like & getrecommendations! Published in 2020 at "Biomaterials science"
DOI: 10.1039/d0bm00162g
Abstract: Pancreatic cancer has a high mortality rate and efforts towards diagnosis and therapy at an early stage are particularly appealing. Recently, a small peptide, BBN7-14, has attracted much attention for its specific binding ability to… read more here.
Keywords: bbn7; novel peptide; pancreatic cancer; cancer ... See more keywords
A novel peptide from the skin of amphibian Rana limnocharis with potency to promote skin wound repair
Sign Up to like & getrecommendations! Published in 2020 at "Natural Product Research"
DOI: 10.1080/14786419.2019.1710702
Abstract: Abstract In clinical trials, the healing of wounds remains a substantial physiological and financial incumbrance on patients. Therefore, the development of new drugs that can accelerate wound healing is vital. Based on genomic methods, we… read more here.
Keywords: rl10; novel peptide; skin; skin amphibian ... See more keywords
Analysis of Therapeutic Targets of A Novel Peptide Athycaltide-1 in the Treatment of Isoproterenol-Induced Pathological Myocardial Hypertrophy
Sign Up to like & getrecommendations! Published in 2022 at "Cardiovascular Therapeutics"
DOI: 10.1155/2022/2715084
Abstract: Myocardial hypertrophy is a pathological feature of many heart diseases. This is a complex process involving all types of cells in the heart and interactions with circulating cells. This study is aimed at identifying the… read more here.
Keywords: myocardial hypertrophy; hypertrophy; peptide athycaltide; analysis ... See more keywords
Synthesis and characterization of a novel peptide-grafted Cs and evaluation of its nanoparticles for the oral delivery of insulin, in vitro, and in vivo study
Sign Up to like & getrecommendations! Published in 2018 at "International Journal of Nanomedicine"
DOI: 10.2147/ijn.s161240
Abstract: Background Despite years of experience and rigorous research, injectable insulin is the sole trusted treatment method to control the blood glucose level in diabetes type 1 patients, but injection of insulin is painful and poses… read more here.
Keywords: insulin; vivo; oral delivery; novel peptide ... See more keywords
The Novel Peptide AEDPPE Alleviates Trophoblast Cell Dysfunction Associated With Preeclampsia by Regulating the NF-κB Signaling Pathway
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Cardiovascular Medicine"
DOI: 10.3389/fcvm.2021.738378
Abstract: Background: Preeclampsia (PE) is a serious risk to the health of pregnant women and fetuses during pregnancy, and there is no effective treatment for this condition. Although many reports have confirmed the therapeutic effects of… read more here.
Keywords: peptide aedppe; signaling pathway; htr svneo; cell ... See more keywords
In Vitro and In Vivo Antimicrobial Activity of the Novel Peptide OMN6 against Multidrug-Resistant Acinetobacter baumannii
Sign Up to like & getrecommendations! Published in 2022 at "Antibiotics"
DOI: 10.3390/antibiotics11091201
Abstract: The rapid worldwide spread of antimicrobial resistance highlights the significant need for the development of innovative treatments to fight multidrug-resistant bacteria. This study describes the potent antimicrobial activity of the novel peptide OMN6 against a… read more here.
Keywords: antimicrobial activity; peptide omn6; activity novel; novel peptide ... See more keywords
A Novel Peptide with Antifungal Activity from Red Swamp Crayfish Procambarus clarkii
Sign Up to like & getrecommendations! Published in 2022 at "Antibiotics"
DOI: 10.3390/antibiotics11121792
Abstract: The defense system of freshwater crayfish Procambarus clarkii as a diversified source of bioactive molecules with antimicrobial properties was studied. Antimicrobial activity of two polypeptide-enriched extracts obtained from hemocytes and hemolymph of P. clarkii were… read more here.
Keywords: crayfish procambarus; procambarus clarkii; activity; novel peptide ... See more keywords
A Novel Peptide-Based Detection of SARS-CoV-2 Antibodies
Sign Up to like & getrecommendations! Published in 2023 at "Biomimetics"
DOI: 10.3390/biomimetics8010089
Abstract: The need for rapidly developed diagnostic tests has gained significant attention after the recent pandemic. Production of neutralizing antibodies for vaccine development or antibodies to be used in diagnostic tests usually require the usage of… read more here.
Keywords: peptide based; detection sars; cov antibodies; novel peptide ... See more keywords