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Published in 2019 at "Journal of Thrombosis and Thrombolysis"
DOI: 10.1007/s11239-019-01933-7
Abstract: Aspirin (acetylsalicylic acid, ASA) can lead to gastrointestinal mucosal injury through disruption of its protective phospholipid bilayer. A liquid formulation of a novel pharmaceutical lipid–aspirin complex (PL-ASA) was designed to prevent this disruption. We sought…
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Keywords:
bioequivalence;
pharmaceutical lipid;
novel pharmaceutical;
aspirin ... See more keywords
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Published in 2021 at "International journal of pharmaceutics"
DOI: 10.1016/j.ijpharm.2021.121394
Abstract: Lenalidomide (LDM), widely used for the treatment of transfusion-dependent anaemia, has low oral bioavailability due to its poor aqueous solubility. Herein, we selected nicotinamide (NIC) as a coformer and synthesized a novel pharmaceutical cocrystal: lenalidomide-nicotinamide…
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Keywords:
pharmaceutical cocrystal;
novel pharmaceutical;
phase transition;
cocrystal lenalidomide ... See more keywords
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Published in 2022 at "RSC Advances"
DOI: 10.1039/d2ra05565a
Abstract: Three novel pharmaceutical salts of cephalexin (CPX) with 2,6-dihydroxybenzoic acid (DHBA), 5-chlorosalicylic acid (CSA) and 5-sulfosalicylic acid (SSA), which were obtained and thoroughly explored by various analytical techniques, were found to be crystallized invariably in…
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Keywords:
organic counterions;
counterions structural;
cephalexin organic;
salts cephalexin ... See more keywords
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Published in 2018 at "International Journal of Applied Pharmaceutics"
DOI: 10.22159/ijap.2018v10i5.26663
Abstract: Objective: Pharmaceutical cocrystal is a promising method to improve the solubility of active pharmaceutical ingredients (APIs). Itraconazole (ITZ) is a BCS class II antifungal drug with poor aqueous solubility, therefore an attempt was made to…
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Keywords:
novel pharmaceutical;
solubility itz;
itz;
solubility ... See more keywords