Aromatase inhibitors and apoptotic inducers: Design, synthesis, anticancer activity and molecular modeling studies of novel phenothiazine derivatives carrying sulfonamide moiety as hybrid molecules.
Sign Up to like & getrecommendations! Published in 2017 at "European journal of medicinal chemistry"
DOI: 10.1016/j.ejmech.2017.04.028
Abstract: Hybrid molecules are used as anticancer agents to improve effectiveness and diminish drug resistance. So, the current study aimed to introduce twenty novel phenothiazine sulfonamide hybrids 5-22, 24 and 25 of promising anticancer activity. Compounds… read more here.
Keywords: hybrid molecules; anticancer activity; effect; novel phenothiazine ... See more keywords
Naked-Eye Chromogenic Test Strip for Cyanide Sensing Based on Novel Phenothiazine Push–Pull Derivatives
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DOI: 10.3390/bios12060407
Abstract: Monitoring and detection of cyanide are of crucial interest as the latter plays versatile roles in many biological events, is ubiquitous in environment, and responsible for several acute poisoning and adverse health effects if ingested.… read more here.
Keywords: push pull; novel phenothiazine; naked eye; cyanide sensing ... See more keywords