Novel Polyamine–Naphthalene Diimide Conjugates Targeting Histone Deacetylases and DNA for Cancer Phenotype Reprogramming
Sign Up to like & getrecommendations! Published in 2017 at "ACS Medicinal Chemistry Letters"
DOI: 10.1021/acsmedchemlett.7b00289
Abstract: A series of hybrid compounds was designed to target histone deacetylases and ds-/G-quadruplex DNAs by merging structural features deriving from Scriptaid and compound 1. Compound 6 binds different DNA arrangements, inhibits HDACs both in vitro… read more here.
Keywords: cancer; novel polyamine; histone deacetylases; phenotype reprogramming ... See more keywords
Preparation of novel polyamine-type chelating resin with hyperbranched structures and its adsorption performance
Sign Up to like & getrecommendations! Published in 2018 at "Royal Society Open Science"
DOI: 10.1098/rsos.171665
Abstract: This paper explored the method of combining atom transfer radical polymerization (ATRP) technology and hyperbranched polymer principle to prepare the high capacity chelating resin. First, surface-initiated atom transfer radical polymerization (SI-ATRP) method was used to… read more here.
Keywords: resin; chelating resin; preparation novel; polyamine type ... See more keywords