Enantiomeric separation of Novel Psychoactive Substances by capillary electrophoresis using (+)-18-crown-6-tetracarboxylic acid as chiral selector.
Sign Up to like & getrecommendations! Published in 2018 at "Chirality"
DOI: 10.1002/chir.22981
Abstract: In the recent years, hundreds of Novel Psychoactive Substances (NPS) have entered both the European and the global drug market. These drugs, which are mainly used for recreational matters, have caused serious social problems. Every… read more here.
Keywords: psychoactive substances; crown tetracarboxylic; enantiomeric separation; tetracarboxylic acid ... See more keywords
Determination of the chiral status of different novel psychoactive substance classes by capillary electrophoresis and β‐cyclodextrin derivatives
Sign Up to like & getrecommendations! Published in 2020 at "Chirality"
DOI: 10.1002/chir.23268
Abstract: Abstract Besides the abuse of well‐known illicit drugs, consumers discovered new synthetic compounds with similar effects but minor alterations in their chemical structure. Originally, these so‐called novel psychoactive substances (NPS) have been created to circumvent… read more here.
Keywords: cyclodextrin; determination chiral; electrophoresis; chiral status ... See more keywords
Development and validation of a rapid LC-MS/MS method for the detection of 182 novel psychoactive substances in whole blood.
Sign Up to like & getrecommendations! Published in 2021 at "Drug testing and analysis"
DOI: 10.1002/dta.3170
Abstract: INTRODUCTION The analysis of novel psychoactive substances (NPS) represents a challenge in forensic toxicology, due to the high number of compounds characterized by different structures and physicochemical properties both among different subclasses and within a… read more here.
Keywords: detection; validation; method; novel psychoactive ... See more keywords
A Simple HPLC–UV Approach for Rapid Enantioseparation of Cathinones, Pyrovalerones and Other Novel Psychoactive Substances on a 2.5-µm Cellulose Tris-(3,5-dimethylphenyl-carbamate) Column
Sign Up to like & getrecommendations! Published in 2020 at "Chromatographia"
DOI: 10.1007/s10337-020-03860-9
Abstract: The misuse of so called novel psychoactive substances is still a challenging problem worldwide. A special attribute of a lot of these compounds is a chiral centre enabling two possible enantiomers probably related to different… read more here.
Keywords: enantioseparation; hplc; column; psychoactive substances ... See more keywords
Discriminative Characteristics of Marginalised Novel Psychoactive Users: a Transnational Study
Sign Up to like & getrecommendations! Published in 2019 at "International Journal of Mental Health and Addiction"
DOI: 10.1007/s11469-019-00128-8
Abstract: New psychoactive substances (NPS) continue to be considered as a major public health concern in many European countries. The study was implemented within the framework of a transnational project of six European countries (Germany, Hungary,… read more here.
Keywords: characteristics marginalised; marginalised novel; discriminative characteristics; psychoactive users ... See more keywords
Virtual ‘Experiential Expert’ Communities of Practice in Sharing Evidence-Based Prevention of Novel Psychoactive Substance (NPS) Use: the Portuguese Experience
Sign Up to like & getrecommendations! Published in 2020 at "International Journal of Mental Health and Addiction"
DOI: 10.1007/s11469-020-00376-z
Abstract: We present findings from a unique virtual community of practice piloted to support a programme of prevention evidence and knowledge sharing among professional prevention practitioners as ‘experiential experts’ around tackling novel psychoactive substances (NPS) use… read more here.
Keywords: evidence; practice; novel psychoactive; prevention ... See more keywords
Combined in Vitro and in Silico Approaches to the Assessment of Stimulant Properties of Novel Psychoactive Substances
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DOI: 10.1016/j.bpj.2016.11.1833
Abstract: Novel psychoactive substances (NPS) are increasingly prevalent world-wide although their pharmacological characteristics are largely unknown; those with stimulant properties, due to interactions with the dopamine transporter (DAT), have addictive potential which their users may not… read more here.
Keywords: psychoactive substances; mapb; novel psychoactive; dat ... See more keywords
Use of Novel Psychoactive Substances and Induced Psychiatric Symptoms: Outcomes From the Eivissa Project
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DOI: 10.1016/j.eurpsy.2017.01.2164
Abstract: Introduction Polydrug abuse seems to be especially popular in Ibiza, an important market for new psychoactive substances (NPS). The misuse of psychoactive substances can lead to serious psychiatric symptoms. Aims To evaluate symptoms induced by… read more here.
Keywords: use novel; psychoactive substances; psychiatric symptoms; novel psychoactive ... See more keywords
Combined in vitro and in silico approaches to the assessment of stimulant properties of novel psychoactive substances – The case of the benzofuran 5-MAPB
Sign Up to like & getrecommendations! Published in 2017 at "Progress in Neuro-Psychopharmacology and Biological Psychiatry"
DOI: 10.1016/j.pnpbp.2016.11.004
Abstract: ABSTRACT Novel psychoactive substances (NPS) are increasingly prevalent world‐wide although their pharmacological characteristics are largely unknown; those with stimulant properties, due to interactions with the dopamine transporter (DAT), have addictive potential which their users may… read more here.
Keywords: dopamine; mapb; novel psychoactive; dat ... See more keywords
Exploring the intersections between novel psychoactive substances (NPS) and other substance use in a police custody suite setting in the north east of England
Sign Up to like & getrecommendations! Published in 2018 at "Drugs: Education, Prevention and Policy"
DOI: 10.1080/09687637.2017.1378620
Abstract: Abstract Aims: Novel psychoactive substances (NPS), a range of plant-based/synthetic substances that mimic effects of other illicit substances (e.g. cannabis), are now illegal in the United Kingdom (May 2016) to produce/supply. Negative behavioural consequences of… read more here.
Keywords: substance; police custody; psychoactive substances; substances nps ... See more keywords
Reports of Adverse Events Associated with Use of Novel Psychoactive Substances, 2017–2020: A Review
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Analytical Toxicology"
DOI: 10.1093/jat/bkac023
Abstract: Abstract An important role of modern forensic and clinical toxicologists is to monitor the adverse events of novel psychoactive substances (NPS). Following a prior review from 2013 to 2016, this critical literature review analyzes and… read more here.
Keywords: psychoactive substances; review; events associated; case ... See more keywords