Articles with "novel quinolinone" as a keyword



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Analysis of two novel 1–4 quinolinone structures with bromine and nitrobenzyl ligands

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Published in 2019 at "Journal of Molecular Modeling"

DOI: 10.1007/s00894-019-3937-3

Abstract: The scientific community has shown particular interest in the study of quinolinones—a class of bicyclic organic compounds. An example of these compounds are the 4-quinolinones, considered to be very useful building blocks, since they can… read more here.

Keywords: novel quinolinone; structures bromine; quinolinone structures; bromine nitrobenzyl ... See more keywords
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QSAR Studies, Molecular Docking, Molecular Dynamics, Synthesis, and Biological Evaluation of Novel Quinolinone-Based Thiosemicarbazones against Mycobacterium tuberculosis

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Published in 2022 at "Antibiotics"

DOI: 10.3390/antibiotics12010061

Abstract: In this study, a series of novel quinolinone-based thiosemicarbazones were designed in silico and their activities tested in vitro against Mycobacterium tuberculosis (M. tuberculosis). Quantitative structure-activity relationship (QSAR) studies were performed using quinolinone and thiosemicarbazide… read more here.

Keywords: mycobacterium tuberculosis; quinolinone; quinolinone based; tuberculosis ... See more keywords