Novel redox-targets of NADPH oxidase 4
Sign Up to like & getrecommendations! Published in 2018 at "Free Radical Biology and Medicine"
DOI: 10.1016/j.freeradbiomed.2018.04.100
Abstract: Nox-derived ROS have been implicated in redox-signaling as they can elicit cysteine oxidation in target proteins. Only a limited number of Nox-differentially oxidized proteins have been identified so far and particularly little is known concerning… read more here.
Keywords: switch assay; biam switch; nadph oxidase; redox targets ... See more keywords
A novel redox cycle diverts cells from oncogene-induced senescence into cancer.
Sign Up to like & getrecommendations! Published in 2021 at "Molecular cell"
DOI: 10.1016/j.molcel.2021.08.023
Abstract: Igelmann et al. report a novel metabolic cycle, which they name HTC, that converts NADH into the key antioxidant factor NADPH. The HTC is repressed by the tumor suppressors p53 and RB, and this determines whether… read more here.
Keywords: diverts cells; senescence; cycle; cycle diverts ... See more keywords