Discovery of novel NO-releasing celastrol derivatives with Hsp90 inhibition and cytotoxic activities.
Sign Up to like & getrecommendations! Published in 2018 at "European journal of medicinal chemistry"
DOI: 10.1016/j.ejmech.2018.10.013
Abstract: To develop multifunctional drugs, a series of celastrol/NO donor hybrids were designed, synthesized and evaluated. The detection of NO release amounts showed that the more NO of these hybrids released, the more tumor cells were… read more here.
Keywords: inhibition; celastrol derivatives; releasing celastrol; celastrol ... See more keywords
One-pot preparation of a novel CO-releasing material based on a CO-releasing molecule@metal-organic framework system.
Sign Up to like & getrecommendations! Published in 2017 at "Chemical communications"
DOI: 10.1039/c7cc03605a
Abstract: A novel CO releasing material has been prepared via a one-pot synthesis-encapsulation strategy using the hierarchical metal organic framework [Zn2(dhtp)] (dhtp = 2,5-dihydroxyterephthalate) as a host of the photoactivable molybdenum tricarbonyl complex [Mo(CNCMe2CO2H)3(CO)3]. read more here.
Keywords: releasing material; metal organic; one pot; novel releasing ... See more keywords