Novel risk genes for systemic lupus erythematosus predicted by random forest classification
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-06516-1
Abstract: Genome-wide association studies have identified risk loci for SLE, but a large proportion of the genetic contribution to SLE still remains unexplained. To detect novel risk genes, and to predict an individual’s SLE risk we… read more here.
Keywords: risk; forest classification; novel risk; random forest ... See more keywords
Novel risk factor for fatal arrhythmia in Brugada syndrome
Sign Up to like & getrecommendations! Published in 2020 at "European Heart Journal"
DOI: 10.1093/ehjci/ehaa946.0735
Abstract: Brugada syndrome (BrS) is a genetic disease associated with increased risk of ventricular fibrillation (VF)/ventricular tachycardia (VT). The VF/VT in BrS occurs more frequently during a night time or at a rest with parasympathetic nerve… read more here.
Keywords: brs; risk; salusin; brugada syndrome ... See more keywords
A novel risk score for severe ARDS patients undergoing ECMO after retrieval from peripheral hospitals
Sign Up to like & getrecommendations! Published in 2018 at "Acta Anaesthesiologica Scandinavica"
DOI: 10.1111/aas.13022
Abstract: Extracorporeal Membrane Oxygenation in severe ARDS unresponsive to conventional protective ventilation is associated with elevated costs, resource and complications, and appropriate risk stratification of candidate patients could be useful to recognize those more likely to… read more here.
Keywords: risk; score severe; risk score; novel risk ... See more keywords
Novel risk factor for valganciclovir toxicity—NUDT15 genetic variant
Sign Up to like & getrecommendations! Published in 2022 at "Transplant Infectious Disease"
DOI: 10.1111/tid.13799
Abstract: Recent “in vitro” studies describe nucleoside diphosphate–linked moiety X-type motif 15 (NUDT15) enzyme to be involved in the metabolismofganciclovir. 1,2 Wereportsevereleukopeniaduringther-apy with valganciclovir in a recent kidney transplant recipient with NUDT15 geneticvariation.Thiscasereportisthefirsttosubstantiatea theoretical postulate of… read more here.
Keywords: factor valganciclovir; toxicity nudt15; valganciclovir toxicity; risk factor ... See more keywords
Tau Mutations as a Novel Risk Factor for Cancer-Letter.
Sign Up to like & getrecommendations! Published in 2018 at "Cancer research"
DOI: 10.1158/0008-5472.can-18-2313
Abstract: Rossi and colleagues (2018) recently reported an increased cancer frequency in 15 families with frontotemporal lobar degeneration (FTLD) and mutations in the microtubule-associated protein tau ( MAPT ) gene (15% of 162 subjects of MAPT… read more here.
Keywords: tau; mutations novel; risk factor; cancer ... See more keywords
Novel Risk Markers and Risk Assessments for Cardiovascular Disease
Sign Up to like & getrecommendations! Published in 2017 at "Circulation Research"
DOI: 10.1161/circresaha.116.309955
Abstract: The use of risk markers has transformed cardiovascular medicine, exemplified by the routine assessment of troponin, for both diagnosis and assessment of prognosis in patients with chest pain. Clinical risk factors form the basis for… read more here.
Keywords: medicine; risk markers; risk; cardiovascular disease ... See more keywords
Targeted Sequencing of Alzheimer Disease Genes in African Americans Implicates Novel Risk Variants
Sign Up to like & getrecommendations! Published in 2018 at "Frontiers in Neuroscience"
DOI: 10.3389/fnins.2018.00592
Abstract: The genetic architecture of late-onset Alzheimer disease (AD) in African Americans (AAs) differs from that in persons of European ancestry. In addition to APOE, genome-wide association studies (GWASs) of AD in AA samples have implicated… read more here.
Keywords: risk; alzheimer disease; african americans; novel risk ... See more keywords
A novel risk classification system based on the eighth edition of TNM frameworks for esophageal adenocarcinoma patients: A deep learning approach
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2022.887841
Abstract: Objective To develop and validate a deep learning predictive model with better performance in survival estimation of esophageal adenocarcinoma (EAC). Method Cases diagnosed between January 2010 and December 2018 were extracted from the Surveillance, Epidemiology,… read more here.
Keywords: risk classification; system; classification system; deep learning ... See more keywords
[Comparison of application effects of colonoscopy, fecal immunochemical test and a novel risk-adapted screening approach in colorectal cancer screening in Xuzhou population].
Sign Up to like & getrecommendations! Published in 2022 at "Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine]"
DOI: 10.3760/cma.j.cn112150-20211203-01113
Abstract: Objective: To compare the application effect of the colonoscopy, fecal immunochemical test (FIT) and novel risk-adapted screening approach in colorectal cancer screening in Xuzhou population. Methods: From May 2018 to April 2019, 4 280 subjects… read more here.
Keywords: adapted screening; group; risk; novel risk ... See more keywords