Novel roles for RNA binding proteins squid, hephaesteus, and Hrb27C in Drosophila oogenesis
Sign Up to like & getrecommendations! Published in 2022 at "Developmental Dynamics"
DOI: 10.1002/dvdy.550
Abstract: Reproductive capacity in many organisms is maintained by germline stem cells (GSCs). A complex regulatory network influences stem cell fate, including intrinsic factors, local signals, and hormonal and nutritional cues. Posttranscriptional regulatory mechanisms ensure proper… read more here.
Keywords: rna binding; novel roles; squid hephaesteus; proteins squid ... See more keywords
Quantitative phosphoproteomics reveals novel roles of cAMP in plants.
Sign Up to like & getrecommendations! Published in 2023 at "Proteomics"
DOI: 10.1002/pmic.202300165
Abstract: 3',5'-cyclic adenosine monophosphate (cAMP) is finally recognized as an essential signaling molecule in plants where cAMP-dependent processes include responses to hormones and environmental stimuli. To better understand the role of 3',5'-cAMP at the systems level,… read more here.
Keywords: quantitative phosphoproteomics; reveals novel; novel roles; camp ... See more keywords
Novel roles for podocalyxin in regulating stress myelopoiesis, Rap1a, and neutrophil migration.
Sign Up to like & getrecommendations! Published in 2017 at "Experimental hematology"
DOI: 10.1016/j.exphem.2017.04.001
Abstract: Podocalyxin (Podxl) is a CD34 orthologue and cell surface sialomucin reported to have roles in renal podocyte diaphragm slit development; vascular cell integrity; and the progression of blood, breast, and prostate cancers. Roles for Podxl… read more here.
Keywords: novel roles; rap1a; stress; podxl ... See more keywords
Novel roles for G protein-coupled receptor kinases in cardiac injury and repair.
Sign Up to like & getrecommendations! Published in 2023 at "Biochemical Society transactions"
DOI: 10.1042/bst20221317
Abstract: G protein-coupled receptors (GPCRs) are key modulators of cell signaling. Multiple GPCRs are present in the heart where they regulate cardiac homeostasis including processes such as myocyte contraction, heart rate and coronary blood flow. GPCRs… read more here.
Keywords: coupled receptor; novel roles; roles protein; heart ... See more keywords
Quantitative Analyses Reveal Novel Roles for N-Glycosylation in a Major Enteric Bacterial Pathogen
Sign Up to like & getrecommendations! Published in 2019 at "mBio"
DOI: 10.1128/mbio.00297-19
Abstract: Advances in genomics and mass spectrometry have revealed several types of glycosylation systems in bacteria. However, why bacterial proteins are modified remains poorly defined. Here, we investigated the role of general N-linked glycosylation in a… read more here.
Keywords: quantitative proteomic; novel roles; proteome stability; glycosylation ... See more keywords
Abstract 2567: Exploring novel roles of the GPCR Smoothened in AKT signaling and drug resistance
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Research"
DOI: 10.1158/1538-7445.am2023-2567
Abstract: The Smoothened receptor (SMO) belongs to the frizzled-class-G-protein coupled receptor and its activity can be classified in the canonical and the non-canonical pathway. The canonical pathway concludes in the transcriptional activation of the Hedgehog target… read more here.
Keywords: drug resistance; receptor; novel roles; akt signaling ... See more keywords
Voltage-gated calcium channel α 2δ subunits: an assessment of proposed novel roles
Sign Up to like & getrecommendations! Published in 2018 at "F1000Research"
DOI: 10.12688/f1000research.16104.1
Abstract: Voltage-gated calcium (CaV) channels are associated with β and α2δ auxiliary subunits. This review will concentrate on the function of the α2δ protein family, which has four members. The canonical role for α2δ subunits is… read more here.
Keywords: calcium channel; gated calcium; novel roles; voltage gated ... See more keywords
Novel Roles of Non-Coding RNAs in Opioid Signaling and Cardioprotection
Sign Up to like & getrecommendations! Published in 2018 at "Non-Coding RNA"
DOI: 10.3390/ncrna4030022
Abstract: Cardiovascular disease (CVD) is a significant cause of morbidity and mortality across the world. A large proportion of CVD deaths are secondary to coronary artery disease (CAD) and myocardial infarction (MI). Even though prevention is… read more here.
Keywords: coding rnas; opioid signaling; novel roles; non coding ... See more keywords