A novel SH2 recognition mechanism recruits Spt6 to the doubly phosphorylated RNA polymerase II linker at sites of transcription
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DOI: 10.7554/elife.28723
Abstract: We determined that the tandem SH2 domain of S. cerevisiae Spt6 binds the linker region of the RNA polymerase II subunit Rpb1 rather than the expected sites in its heptad repeat domain. The 4 nM… read more here.
Keywords: spt6; sites transcription; sh2; rna polymerase ... See more keywords