Mechanisms of Vascular Dysfunction in COPD and Effects of a Novel Soluble Epoxide Hydrolase Inhibitor in Smokers
Sign Up to like & getrecommendations! Published in 2017 at "Chest"
DOI: 10.1016/j.chest.2016.10.058
Abstract: BACKGROUND: Smoking and COPD are risk factors for cardiovascular disease, and the pathogenesis may involve endothelial dysfunction. We tested the hypothesis that endothelium‐derived epoxyeicosatrienoic acid (EET)‐mediated endothelial function is impaired in patients with COPD and… read more here.
Keywords: soluble epoxide; patients copd; novel soluble; epoxide hydrolase ... See more keywords
A Novel Soluble ACE2 Protein Provides Lung and Kidney Protection in Mice Susceptible to Lethal SARS-CoV-2 Infection.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of the American Society of Nephrology : JASN"
DOI: 10.1681/asn.2021091209
Abstract: Background: Severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2) uses full-length angiotensin converting enzyme 2 (ACE2) as a main receptor to enter target cells. The goal of this study was to demonstrate the preclinical efficacy… read more here.
Keywords: novel soluble; ace2 protein; soluble ace2; sars cov ... See more keywords